DeepCap-Kcr: accurate identification and investigation of protein lysine crotonylation sites based on capsule network

Abstract Lysine crotonylation (Kcr) is a posttranslational modification widely detected in histone and nonhistone proteins. It plays a vital role in human disease progression and various cellular processes, including cell cycle, cell organization, chromatin remodeling and a key mechanism to increase...

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Veröffentlicht in:	Briefings in bioinformatics 2022-01, Vol.23 (1)
Hauptverfasser:	Khanal, Jhabindra, Tayara, Hilal, Zou, Quan, To Chong, Kil
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Artificial neural networks Cell cycle Chromatin remodeling Computer applications Deep learning Drug development Histones Histones - metabolism Humans Learning Long short-term memory Lysine Lysine - metabolism Mammals - metabolism Neural networks Neural Networks, Computer Nonhistone proteins Protein Processing, Post-Translational Proteins Proteomics Software Source code
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