Robust clinical detection of SARS‐CoV‐2 variants by RT‐PCR/MALDI‐TOF multitarget approach

The coronavirus disease 2019 (COVID‐19) pandemic has sparked the rapid development of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) diagnostics. However, emerging variants pose the risk for target dropout and false‐negative results secondary to primer/probe binding site (PBS) mismatch...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of medical virology 2022-04, Vol.94 (4), p.1606-1616
Hauptverfasser:	Hernandez, Matthew M., Banu, Radhika, Gonzalez‐Reiche, Ana S., Guchte, Adriana, Khan, Zenab, Shrestha, Paras, Cao, Liyong, Chen, Feng, Shi, Huanzhi, Hanna, Ayman, Alshammary, Hala, Fabre, Shelcie, Amoako, Angela, Obla, Ajay, Alburquerque, Bremy, Patiño, Luz Helena, Ramírez, Juan David, Sebra, Robert, Gitman, Melissa R., Nowak, Michael D., Cordon‐Cardo, Carlos, Schutzbank, Ted E., Simon, Viviana, Bakel, Harm, Sordillo, Emilia Mia, Paniz‐Mondolfi, Alberto E.
Format:	Artikel
Sprache:	eng
Schlagworte:	B.1.1.7 Binding sites Coronavirus Nucleocapsid Proteins - genetics Coronaviruses COVID-19 COVID-19 - epidemiology COVID-19 - virology COVID-19 Nucleic Acid Testing - methods diagnostic Diagnostic systems dropout Genetic Variation Genome, Viral - genetics Humans Ionization MALDI‐TOF New York City - epidemiology Pandemics Phosphoproteins - genetics Polymerase chain reaction Polyproteins - genetics Redundancy Reverse Transcriptase Polymerase Chain Reaction RNA, Viral - genetics Robustness RT‐PCR SARS-CoV-2 - genetics SARS-CoV-2 - isolation & purification SARS‐CoV‐2 Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Spectrometry Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Substitution reactions variants Viral diseases Viral Proteins - genetics Virology Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!