Drosophila as a model to study autophagy in neurodegenerative diseases and digestive tract

Autophagy regulates cellular homeostasis by degrading and recycling cytosolic components and damaged organelles. Disruption of autophagic flux has been shown to induce or facilitate neurodegeneration and accumulation of autophagic vesicles is overt in neurodegenerative diseases. The fruit fly Drosop...

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Veröffentlicht in:	IUBMB life 2022-04, Vol.74 (4), p.339-360
Hauptverfasser:	Tzou, Fei‐Yang, Wen, Jung‐Kun, Yeh, Jui‐Yu, Huang, Shu‐Yi, Chen, Guang‐Chao, Chan, Chih‐Chiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Autophagy Charcot-Marie-Tooth disease digestive tract Drosophila Energy balance Food intake Gastrointestinal tract Homeostasis Insects Movement disorders Neurodegeneration Neurodegenerative diseases Neuropathy Organelles Parkinson's disease Physiology Polyglutamine Trinucleotide repeat diseases
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