The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

Lung adenocarcinoma (LUAD) is the leading cause of cancer deaths worldwide due to the lack of early diagnostic markers and specific drugs. Previous studies have shown the association of LUAD growth with aberrant alternative splicing (AS). Herein, clinical data of 535 tumor tissues and 59 normal tiss...

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Veröffentlicht in:	BMC pulmonary medicine 2021-12, Vol.21 (1), p.400-400, Article 400
Hauptverfasser:	Wang, Gongjun, Qi, Weiwei, Shen, Liwei, Wang, Shasha, Xiao, Ruoxi, Li, Wenqian, Zhang, Yuqi, Bian, Xiaoqian, Sun, Libin, Qiu, Wensheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma of Lung - genetics Adenocarcinoma of Lung - immunology Adenocarcinoma of Lung - mortality Adenocarcinoma of Lung - pathology Algorithms Alternative splicing Alternative Splicing - genetics Alternative Splicing - immunology Bioinformatics Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics Biomarkers, Tumor - immunology Cancer Carcinogenesis China Databases, Genetic Development and progression Disease-Free Survival Drug development Gene expression Genetic aspects Genomes Humans Immune Immunology Immunosuppressive agents LUAD Lung cancer Lung Neoplasms - genetics Lung Neoplasms - immunology Lung Neoplasms - mortality Lung Neoplasms - pathology Medical prognosis Metastases Oncology, Experimental Prognosis Pulmonology Risk Assessment - methods Risk groups RNA splicing Survival Rate Therapeutic targets Tumor microenvironment Tumor Microenvironment - genetics Tumor Microenvironment - immunology Tumorigenesis
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