Improving CRISPR tools by elucidating DNA repair
Genome-editing tools are optimized by identifying genes that affect DNA repair.
Gespeichert in:
Veröffentlicht in: | Nature biotechnology 2021-12, Vol.39 (12), p.1512-1514 |
---|---|
Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 1514 |
---|---|
container_issue | 12 |
container_start_page | 1512 |
container_title | Nature biotechnology |
container_volume | 39 |
creator | Lim, Jung Min Kim, Hyongbum Henry |
description | Genome-editing tools are optimized by identifying genes that affect DNA repair. |
doi_str_mv | 10.1038/s41587-021-01149-2 |
format | Article |
fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2607591192</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A686656138</galeid><sourcerecordid>A686656138</sourcerecordid><originalsourceid>FETCH-LOGICAL-c498t-38710cbde9625dd47d9201f4121703512c813362b2ab0a9afd43455162730973</originalsourceid><addsrcrecordid>eNqNkltLHTEUhUOpqLX-gT7IgC8tdGx2rpPHw-nFA1LlKH0NmZnMGJnLMZkp9d8301HrKSIlkITsb61sNguhd4BPANPsU2DAM5liAikGYColr9A-cCZSEEq8jnc8lYGLPfQmhBuMsWBC7KI9yjJJKZH7CK_aje9_uq5OluvV5cU6Gfq-CUl-l9hmLFxphqn2-fsi8XZjnH-LdirTBHt4fx6gq69frpan6dn5t9VycZYWTGVDSjMJuMhLqwThZclkqQiGigEBiSkHUmRAqSA5MTk2ylQlo4xzEERSrCQ9QO9n29jd7WjDoFsXCts0prP9GDQRWHIFoEhEj_9Bb_rRd7G5iVKccIh_PVK1aax2XdUP3hSTqV6ITAgugGaROnmGiqu0rSv6zlYuvm8JPmwJIjPYX0NtxhD06nL9_-z5j2324xM2H4PrbIhbcPX1EGbJFk5mvPB9CN5WeuNda_ydBqynsOg5LDqGRf8Ji54Gd3Q_uDFvbfkoeUhHBOgMhFjqauv_TvYF2986oMHe</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2609525181</pqid></control><display><type>article</type><title>Improving CRISPR tools by elucidating DNA repair</title><source>MEDLINE</source><source>Nature</source><source>Alma/SFX Local Collection</source><creator>Lim, Jung Min ; Kim, Hyongbum Henry</creator><creatorcontrib>Lim, Jung Min ; Kim, Hyongbum Henry</creatorcontrib><description>Genome-editing tools are optimized by identifying genes that affect DNA repair.</description><identifier>ISSN: 1087-0156</identifier><identifier>EISSN: 1546-1696</identifier><identifier>DOI: 10.1038/s41587-021-01149-2</identifier><identifier>PMID: 34873327</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>631/1647/1511 ; 631/1647/1513/1967 ; 631/1647/2163 ; 631/208/514 ; Agriculture ; Analysis ; Bioinformatics ; Biomedical and Life Sciences ; Biomedical Engineering/Biotechnology ; Biomedicine ; Biotechnology ; Clustered Regularly Interspaced Short Palindromic Repeats - genetics ; CRISPR ; CRISPR-Cas Systems - genetics ; Deoxyribonucleic acid ; DNA ; DNA repair ; DNA Repair - genetics ; Gene Editing ; Genes ; Genome editing ; Genomes ; Identification and classification ; Life Sciences ; News & Views ; news-and-views ; Repair</subject><ispartof>Nature biotechnology, 2021-12, Vol.39 (12), p.1512-1514</ispartof><rights>Springer Nature America, Inc. 2021</rights><rights>COPYRIGHT 2021 Nature Publishing Group</rights><rights>Springer Nature America, Inc. 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c498t-38710cbde9625dd47d9201f4121703512c813362b2ab0a9afd43455162730973</cites><orcidid>0000-0002-4693-738X ; 0000-0002-0223-5933</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34873327$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lim, Jung Min</creatorcontrib><creatorcontrib>Kim, Hyongbum Henry</creatorcontrib><title>Improving CRISPR tools by elucidating DNA repair</title><title>Nature biotechnology</title><addtitle>Nat Biotechnol</addtitle><addtitle>Nat Biotechnol</addtitle><description>Genome-editing tools are optimized by identifying genes that affect DNA repair.</description><subject>631/1647/1511</subject><subject>631/1647/1513/1967</subject><subject>631/1647/2163</subject><subject>631/208/514</subject><subject>Agriculture</subject><subject>Analysis</subject><subject>Bioinformatics</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedical Engineering/Biotechnology</subject><subject>Biomedicine</subject><subject>Biotechnology</subject><subject>Clustered Regularly Interspaced Short Palindromic Repeats - genetics</subject><subject>CRISPR</subject><subject>CRISPR-Cas Systems - genetics</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA repair</subject><subject>DNA Repair - genetics</subject><subject>Gene Editing</subject><subject>Genes</subject><subject>Genome editing</subject><subject>Genomes</subject><subject>Identification and classification</subject><subject>Life Sciences</subject><subject>News & Views</subject><subject>news-and-views</subject><subject>Repair</subject><issn>1087-0156</issn><issn>1546-1696</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>N95</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkltLHTEUhUOpqLX-gT7IgC8tdGx2rpPHw-nFA1LlKH0NmZnMGJnLMZkp9d8301HrKSIlkITsb61sNguhd4BPANPsU2DAM5liAikGYColr9A-cCZSEEq8jnc8lYGLPfQmhBuMsWBC7KI9yjJJKZH7CK_aje9_uq5OluvV5cU6Gfq-CUl-l9hmLFxphqn2-fsi8XZjnH-LdirTBHt4fx6gq69frpan6dn5t9VycZYWTGVDSjMJuMhLqwThZclkqQiGigEBiSkHUmRAqSA5MTk2ylQlo4xzEERSrCQ9QO9n29jd7WjDoFsXCts0prP9GDQRWHIFoEhEj_9Bb_rRd7G5iVKccIh_PVK1aax2XdUP3hSTqV6ITAgugGaROnmGiqu0rSv6zlYuvm8JPmwJIjPYX0NtxhD06nL9_-z5j2324xM2H4PrbIhbcPX1EGbJFk5mvPB9CN5WeuNda_ydBqynsOg5LDqGRf8Ji54Gd3Q_uDFvbfkoeUhHBOgMhFjqauv_TvYF2986oMHe</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Lim, Jung Min</creator><creator>Kim, Hyongbum Henry</creator><general>Nature Publishing Group US</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>N95</scope><scope>XI7</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QO</scope><scope>7QP</scope><scope>7QR</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>M7S</scope><scope>MBDVC</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-4693-738X</orcidid><orcidid>https://orcid.org/0000-0002-0223-5933</orcidid></search><sort><creationdate>20211201</creationdate><title>Improving CRISPR tools by elucidating DNA repair</title><author>Lim, Jung Min ; Kim, Hyongbum Henry</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498t-38710cbde9625dd47d9201f4121703512c813362b2ab0a9afd43455162730973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>631/1647/1511</topic><topic>631/1647/1513/1967</topic><topic>631/1647/2163</topic><topic>631/208/514</topic><topic>Agriculture</topic><topic>Analysis</topic><topic>Bioinformatics</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedical Engineering/Biotechnology</topic><topic>Biomedicine</topic><topic>Biotechnology</topic><topic>Clustered Regularly Interspaced Short Palindromic Repeats - genetics</topic><topic>CRISPR</topic><topic>CRISPR-Cas Systems - genetics</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA repair</topic><topic>DNA Repair - genetics</topic><topic>Gene Editing</topic><topic>Genes</topic><topic>Genome editing</topic><topic>Genomes</topic><topic>Identification and classification</topic><topic>Life Sciences</topic><topic>News & Views</topic><topic>news-and-views</topic><topic>Repair</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lim, Jung Min</creatorcontrib><creatorcontrib>Kim, Hyongbum Henry</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale Business: Insights</collection><collection>Business Insights: Essentials</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Nature biotechnology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lim, Jung Min</au><au>Kim, Hyongbum Henry</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Improving CRISPR tools by elucidating DNA repair</atitle><jtitle>Nature biotechnology</jtitle><stitle>Nat Biotechnol</stitle><addtitle>Nat Biotechnol</addtitle><date>2021-12-01</date><risdate>2021</risdate><volume>39</volume><issue>12</issue><spage>1512</spage><epage>1514</epage><pages>1512-1514</pages><issn>1087-0156</issn><eissn>1546-1696</eissn><abstract>Genome-editing tools are optimized by identifying genes that affect DNA repair.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>34873327</pmid><doi>10.1038/s41587-021-01149-2</doi><tpages>3</tpages><orcidid>https://orcid.org/0000-0002-4693-738X</orcidid><orcidid>https://orcid.org/0000-0002-0223-5933</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1087-0156 |
ispartof | Nature biotechnology, 2021-12, Vol.39 (12), p.1512-1514 |
issn | 1087-0156 1546-1696 |
language | eng |
recordid | cdi_proquest_miscellaneous_2607591192 |
source | MEDLINE; Nature; Alma/SFX Local Collection |
subjects | 631/1647/1511 631/1647/1513/1967 631/1647/2163 631/208/514 Agriculture Analysis Bioinformatics Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology Clustered Regularly Interspaced Short Palindromic Repeats - genetics CRISPR CRISPR-Cas Systems - genetics Deoxyribonucleic acid DNA DNA repair DNA Repair - genetics Gene Editing Genes Genome editing Genomes Identification and classification Life Sciences News & Views news-and-views Repair |
title | Improving CRISPR tools by elucidating DNA repair |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T00%3A58%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Improving%20CRISPR%20tools%20by%20elucidating%20DNA%20repair&rft.jtitle=Nature%20biotechnology&rft.au=Lim,%20Jung%20Min&rft.date=2021-12-01&rft.volume=39&rft.issue=12&rft.spage=1512&rft.epage=1514&rft.pages=1512-1514&rft.issn=1087-0156&rft.eissn=1546-1696&rft_id=info:doi/10.1038/s41587-021-01149-2&rft_dat=%3Cgale_proqu%3EA686656138%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2609525181&rft_id=info:pmid/34873327&rft_galeid=A686656138&rfr_iscdi=true |