A comparative study of data‐dependent acquisition and data‐independent acquisition in proteomics analysis of clinical lung cancer tissues constrained by blood contamination

Proteomics analysis is often troubled by high‐abundance proteins in samples such as plasma. However, many surgical tissue samples inevitably have got contaminated with blood before cryopreservation. Selection of an appropriate method to minimize the effect of high‐abundance proteins is important for...

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Veröffentlicht in:	Proteomics (Weinheim) 2022-05, Vol.16 (3), p.e2000099-n/a
Hauptverfasser:	Su, Tao, Zhong, Yi, Zeng, Weibiao, Zhang, Yong, Wang, Shisheng, Cheng, Jingqiu, Yang, Hao, Wei, Yiping, Gong, Meng
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood blood contamination Carcinoma Comparative studies Contamination contamination index Cryopreservation data‐dependent acquisition data‐independent acquisition differential proteins Humans Lung cancer Lung carcinoma Lung Neoplasms - diagnosis Lung Neoplasms - genetics Lung Neoplasms - metabolism Proteins Proteome - metabolism Proteomics Proteomics - methods surgical tissue samples Tissues
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