Single-cell characterization of dog allergen–specific T cells reveals TH2 heterogeneity in allergic individuals

Allergen-specific type 2 CD4+ TH2 cells are critically involved in the pathogenesis of IgE-mediated allergic diseases. However, the heterogeneity of the TH2 response has only recently been appreciated. We sought to characterize at the single-cell level the ex vivo phenotype, transcriptomic profile,...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2022-05, Vol.149 (5), p.1732-1743.e15
Hauptverfasser:	Vandamme, Céline, Rytkönen-Nissinen, Marja, Lönnberg, Tapio, Randell, Jukka, Harvima, Rauno J., Kinnunen, Tuure, Virtanen, Tuomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Can f 1 Can f 4 Can f 5 CD154 dog allergy T cell TH2 TH2A cell
Online-Zugang:	Volltext
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