Oxidative stress-responsive apoptosis inducing protein (ORAIP) plays a critical role in doxorubicin-induced apoptosis in rat cardiac myocytes

Oxidative stress is implicated in the pathogenesis of doxorubicin-induced apoptosis in cardiac myocytes. However, the precise mechanism remains uncertain. We identified an apoptosis-inducing humoral factor, in a conditioned medium from cardiac myocytes subjected to hypoxia/reoxygenation, to be 69th...

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Veröffentlicht in:	International journal of cardiology 2022-02, Vol.348, p.119-124
Hauptverfasser:	Yao, Takako, Fujimura, Tsutomu, Murayama, Kimie, Okumura, Ko, Seko, Yoshinori
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis Regulatory Proteins Cardiac myocytes Doxorubicin Eukaryotic translation initiation factor 5A (eIF5A) Myocytes, Cardiac - metabolism Oxidative Stress Oxidative stress-responsive apoptosis inducing protein (ORAIP) Rats
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