Guiding Transition Metal‐Doped Hollow Cerium Tandem Nanozymes with Elaborately Regulated Multi‐Enzymatic Activities for Intensive Chemodynamic Therapy

Clinical applications of nanozyme‐initiated chemodynamic therapy (NCDT) have been severely limited by the poor catalytic efficiency of nanozymes, insufficient endogenous hydrogen peroxide (H2O2) content, and its off‐target consumption. Herein, the authors developed a hollow mesoporous Mn/Zr‐co‐doped...

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Veröffentlicht in:	Advanced materials (Weinheim) 2022-02, Vol.34 (7), p.e2107054-n/a
Hauptverfasser:	Dong, Shuming, Dong, Yushan, Liu, Bin, Liu, Jing, Liu, Shikai, Zhao, Zhiyu, Li, Wenting, Tian, Boshi, Zhao, Ruoxi, He, Fei, Gai, Shili, Xie, Ying, Yang, Piaoping, Zhao, Yanli
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Attenuation Biocompatibility cancer treatment Catalase Catalysis Cerium Cerium oxides chemodynamic therapy Computed tomography Depletion Glutathione hollow cerium Homeostasis homeostasis disruptor Humans Hydrogen peroxide Hydrogen Peroxide - therapeutic use Hydroxyl Radical Hydroxyl radicals Magnetic resonance imaging Materials science Neoplasms - drug therapy Peroxidase Superoxide dismutase tandem nanozymes Transition metals Tumors Zirconium
Online-Zugang:	Volltext
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