Leptin coordinates efferent sympathetic outflow to the white adipose tissue through the midbrain centrally-projecting Edinger-Westphal nucleus in male rats

The centrally-projecting Edinger-Westphal nucleus (EWcp) hosts a large population of neurons expressing urocortin 1 (Ucn1) and about half of these neurons also express the leptin receptor (LepRb). Previously, we have shown that the peripheral adiposity hormone leptin signaling energy surfeit modulat...

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Veröffentlicht in:	Neuropharmacology 2022-03, Vol.205, p.108898-108898, Article 108898
Hauptverfasser:	Xu, Lu, Füredi, Nóra, Lutter, Christoph, Geenen, Bram, Pétervári, Erika, Balaskó, Márta, Dénes, Ádám, Kovács, Krisztina J., Gaszner, Balázs, Kozicz, Tamás
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue, White - metabolism Animals Edinger-Westphal Nucleus - metabolism Energy metabolism Herpesvirus 1, Suid Leptin - metabolism Leptin receptor Male Pseudorabies virus Rats Receptors, Leptin - metabolism STAT3 STAT3 Transcription Factor - metabolism Sympathetic Nervous System - metabolism Urocortin 1 Urocortins - metabolism
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