Essential role of Msx1 in regulating anterior-posterior patterning of the secondary palate in mice

Development of the secondary palate displays molecular heterogeneity along the anterior-posterior axis; however, the underlying molecular mechanism remains largely unknown. MSX1 is an anteriorly expressed transcription repressor required for palate development. Here, we investigate the role of Msx1...

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Veröffentlicht in:	Journal of genetics and genomics 2022-01, Vol.49 (1), p.63-73
Hauptverfasser:	Zhu, Shicheng, Song, Hanjing, Zhong, Liangjun, Huo, Suman, Fang, Yukun, Zhao, Wanxin, Yang, Xueqin, Dai, Zhong-Min, He, Rui, Qiu, Mengsheng, Zhang, Zunyi, Zhu, Xiao-Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cleft palate Cleft Palate - genetics Cleft Palate - metabolism Conditional knock-in Gene Expression Regulation, Developmental Mesoderm - metabolism Mice Mouse model Msx1 MSX1 Transcription Factor - genetics MSX1 Transcription Factor - metabolism Organ development Transcription Factors - genetics
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