Systematic review and meta-analysis of randomized controlled trials comparing elective neck dissection versus sentinel lymph node biopsy in early-stage clinically node-negative oral and/or oropharyngeal squamous cell carcinoma: Evidence-base for practice and implications for research

•Management of node-negative neck in early-stage oral cancer has been debatable.•Nearly 20-30% of such patients harbour occult metastases in draining lymph nodes.•The N0 neck is usually addressed with elective neck dissection or watchful waiting.•Sentinel lymph node biopsy is an intermediate approac...

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Veröffentlicht in:	Oral oncology 2022-01, Vol.124, p.105642-105642, Article 105642
Hauptverfasser:	Gupta, Tejpal, Maheshwari, Guncha, Kannan, Sadhana, Nair, Sudhir, Chaturvedi, Pankaj, Agarwal, Jai Prakash
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Squamous Cell - pathology Head and Neck Neoplasms Humans Mouth Neoplasms - pathology Mouth Neoplasms - surgery Neck Dissection Observation Oral cancer Randomized Controlled Trials as Topic Sentinel Lymph Node Biopsy Sentinel node Squamous Cell Carcinoma of Head and Neck - surgery Survival
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