Opto-vTrap, an optogenetic trap for reversible inhibition of vesicular release, synaptic transmission, and behavior

Spatiotemporal control of brain activity by optogenetics has emerged as an essential tool to study brain function. For silencing brain activity, optogenetic probes, such as halorhodopsin and archaerhodopsin, inhibit transmitter release indirectly by hyperpolarizing membrane potentials. However, thes...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2022-02, Vol.110 (3), p.423-435.e4
Hauptverfasser:	Won, Joungha, Pankratov, Yuriy, Jang, Minwoo Wendy, Kim, Sunpil, Ju, Yeon Ha, Lee, Sangkyu, Lee, Seung Eun, Kim, Arie, Park, Soowon, Lee, C. Justin, Heo, Won Do
Format:	Artikel
Sprache:	eng
Schlagworte:	CIBN CRY2 exocytosis inhibition lariat Opto-vTrap optogenetic inhibition optogenetics vesicular release inhibition
Online-Zugang:	Volltext
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