Metabolism of Subchondral Bone Tissue in Posttraumatic Osteoarthrosis in Rats

In rats with modeled posttraumatic knee osteoarthrosis, negative changes in subchondral bone metabolism were revealed: a tendency to an increase in osteocalcin concentration, a decrease in sclerostin and osteoprotegerin levels, and a significant increase in FGF-23 concentration accompanied by a slig...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2021-12, Vol.172 (2), p.206-209
Hauptverfasser:	Zubavlenko, R. А., Belova, S. V., Ulyanov, V. Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Outbred Strains Biomedical and Life Sciences Biomedicine Bone and Bones - metabolism Bone and Bones - pathology Bone turnover Calcium - metabolism Cartilage Cartilage, Articular - metabolism Cell Biology Disease Models, Animal Experimental Methods for Clinical Practice Fibroblast growth factor 23 Fibroblast growth factors Internal Medicine Knee Injuries - complications Knee Injuries - metabolism Knee Injuries - pathology Knee Joint - metabolism Knee Joint - pathology Laboratory Medicine Male Medical research Medicine, Experimental Metabolism Osteoarthritis Osteoarthritis, Knee - etiology Osteoarthritis, Knee - metabolism Osteoarthritis, Knee - pathology Osteocalcin Osteocalcin - metabolism Osteoprotegerin Osteoprotegerin - metabolism Pathology Phosphorus - metabolism Physiological aspects Rats SOST protein Subchondral bone
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