Mitochondrial DNA and Alzheimer’s disease: a first case–control study of the Tunisian population

Background Alzheimer’s disease (AD) is the most common neurodegenerative disorder in humans and presents a major health problem throughout the world. The etiology of AD is complex, and many factors are implicated, including mitochondria. Mitochondrial alteration has been proposed as a possible cause...

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Veröffentlicht in:	Molecular biology reports 2022-03, Vol.49 (3), p.1687-1700
Hauptverfasser:	Ben Salem, Nesrine, Boussetta, Sami, de Rojas, Itziar, Moreno-Grau, Sonia, Montrreal, Laura, Mokni, Narjes, Mahmoud, Imene, Younes, Samia, Daouassi, Nizar, Frih-Ayed, Mahbouba, Hammami, Afef, Ben Ammar Elgaaied, Amel, Ruiz, Agustín, Cherni, Lotfi
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Alzheimer Disease - epidemiology Alzheimer Disease - genetics Alzheimer's disease Animal Anatomy Animal Biochemistry Apolipoprotein E Apolipoprotein E4 - genetics Apolipoproteins E - genetics Biomedical and Life Sciences Case-Control Studies DNA, Mitochondrial - genetics Etiology Genetic Predisposition to Disease Genotype Genotyping Histology Humans Life Sciences Mitochondria - genetics Mitochondrial DNA Morphology Neurodegenerative diseases Original Article Pathogenicity Polymorphism, Single Nucleotide - genetics Population studies Risk factors Single-nucleotide polymorphism Tunisia - epidemiology
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