Clinicopathological significance of claspin overexpression and its efficacy as a novel biomarker for the diagnosis of urothelial carcinoma

We previously reported that claspin is a key regulator in the progression of gastric cancer and renal cell carcinoma. However, the clinicopathological significance of claspin in urothelial carcinoma (UC) has not been investigated. We analyzed the expression and distribution of claspin in UC cases by...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2022-03, Vol.480 (3), p.621-633
Hauptverfasser:	Kobayashi, Go, Hayashi, Tetsutaro, Sentani, Kazuhiro, Babasaki, Takashi, Sekino, Yohei, Inoue, Shogo, Uraoka, Naohiro, Hanamoto, Masanori, Nose, Hiroyuki, Teishima, Jun, Oue, Naohide, Matsubara, Akio, Sasaki, Naomi, Yasui, Wataru
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biomarkers - analysis Biomarkers, Tumor - analysis Biopsy Bladder cancer Cancer Carcinoma, Transitional Cell - pathology Chemotherapy Cytology Dysplasia ErbB-2 protein Gastric cancer Histology Humans Immunocytochemistry Immunohistochemistry Kidney cancer Kidney Neoplasms - pathology Medical diagnosis Medicine Medicine & Public Health Original Article Pathology PD-L1 protein Renal cell carcinoma Staining Survival Therapeutic targets Tumors Urinary Bladder Neoplasms - pathology Urothelial carcinoma Urothelium Urothelium - pathology
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