Cyanidin‐3‐O‐Glucoside Supplementation Ameliorates Metabolic Insulin Resistance via Restoration of Nitric Oxide‐Mediated Endothelial Insulin Transport

Scope Anthocyanin cyanidin‐3‐O‐glucoside (Cy3G) possesses a great potential in prevention of diabetes and its vascular complications while the underlying mechanisms are still far from clear. Accumulating evidence suggests that endothelial insulin transport plays a critical role in regulating metabol...

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Veröffentlicht in:	Molecular nutrition & food research 2022-01, Vol.66 (2), p.e2100742-n/a
Hauptverfasser:	Geng, Xiuwen, Ji, Jiajun, Liu, Yuanhua, Li, Xueyan, Chen, Yunan, Su, Lei, Zhao, Lina
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Animals Anthocyanins Anthocyanins - metabolism Anthocyanins - pharmacology Aorta Cell culture Complications cyanidin‐3‐O‐glucoside Cytokines Diabetes mellitus Dietary Supplements Endothelial Cells Glucose metabolism Glucose transport Glucosides Glucosides - metabolism Glucosides - pharmacology High fat diet Inflammation Insulin Insulin - metabolism Insulin Resistance insulin transport Metabolism Mice Muscles Nitric oxide Nitric Oxide - metabolism Nitric Oxide Synthase Type III - metabolism Palmitic acid Signal transduction Skeletal muscle TLR4 protein Toll-like receptors
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