Solid-phase recombinase polymerase amplification using ferrocene-labelled dNTPs for electrochemical detection of single nucleotide polymorphisms

Hypertrophic cardiomyopathies (HCM) are the principal cause of sudden cardiac death in young athletes and it is estimated that 1 in 500 people have HCM. The aim of this work was to develop an electrochemical platform for the detection of HCM-associated SNP in the Myosin Heavy Chain 7 (MYH7) gene, in...

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Veröffentlicht in:	Biosensors & bioelectronics 2022-02, Vol.198, p.113825-113825, Article 113825
Hauptverfasser:	Ortiz, Mayreli, Jauset-Rubio, Miriam, Kodr, David, Simonova, Anna, Hocek, Michal, O'Sullivan, Ciara K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensing Techniques Biosensors DNA - genetics Electrochemical detection Ferrocene-dNTPs Fingerprick Humans Metallocenes Polymorphism, Single Nucleotide Recombinases - genetics SNP Solid phase recombinase polymerase amplification
Online-Zugang:	Volltext
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