Identification and a phased pH control strategy of diosgenin bio-synthesized by an endogenous Bacillus licheniformis Syt1 derived from Dioscorea zingiberensis C. H. Wright

Diosgenin is widely used as one precursor of steroidal drugs in pharmaceutical industry. Currently, there is no choice but to traditionally extract diosgenin from Dioscorea zingiberensis C. H. Wright ( DZW ) or other plants. In this work, an environmentally friendly approach, in which diosgenin can...

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Veröffentlicht in:	Applied microbiology and biotechnology 2021-12, Vol.105 (24), p.9333-9342
Hauptverfasser:	Hu, Zhongqiu, Wang, Chunli, Pan, Lintao, Han, Shiyao, Jin, Miao, Xiang, Yongsheng, Zheng, Lifei, Li, Zhonghong, Cao, Rang, Qin, Baofu
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus (Bacteria) Bacillus licheniformis Biomedical and Life Sciences Biosynthesis Biotechnology Chloroform Cholesterol Dioscorea zingiberensis Drugs Endophytes Fermentation Fourier analysis Fourier transforms Gravimetric analysis Handedness Health aspects High performance liquid chromatography Infrared analysis Infrared spectroscopy Life Sciences Liquid chromatography Melting point Melting points Methods Methods and Protocols Microbial Genetics and Genomics Microbiology NMR Nuclear magnetic resonance Optical properties Optical rotation pH control pH effects Pharmaceutical industry Physiological aspects Steroids Thermal analysis Yams
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