KATNB1 is a master regulator of multiple katanin enzymes in male meiosis and haploid germ cell development

Katanin microtubule-severing enzymes are crucial executers of microtubule regulation. Here, we have created an allelic loss-of-function series of the katanin regulatory B-subunit KATNB1 in mice. We reveal that KATNB1 is the master regulator of all katanin enzymatic A-subunits during mammalian sperma...

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Veröffentlicht in:Development (Cambridge) 2021-12, Vol.148 (24)
Hauptverfasser: Dunleavy, Jessica E M, O'Connor, Anne E, Okuda, Hidenobu, Merriner, D Jo, O'Bryan, Moira K
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Sprache:eng
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