The Application of Biocatalysis in the Preparation and Resolution of Morita‐Baylis‐Hillman Adducts and Their Derivatives

The Morita‐Baylis‐Hillman (MBH) reaction affords highly functionalised allylic alcohols containing a new stereogenic centre. These MBH adducts are very versatile and have been transformed into a large range of products, some of which have medicinal potential. Several examples of asymmetric syntheses...

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Veröffentlicht in:	Chembiochem : a European journal of chemical biology 2022-04, Vol.23 (7), p.e202100527-n/a
Hauptverfasser:	Juma, Wanyama Peter, Nyoni, Dubekile, Brady, Dean, Bode, Moira L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adducts Alcohols asymmetric synthesis Asymmetry Biocatalysis Catalysis enzymatic kinetic resolution Enzymes Esterases Morita-Baylis-Hillman reaction Selectivity
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