Melatonin and Pathological Cell Interactions: Mitochondrial Glucose Processing in Cancer Cells

Melatonin is synthesized in the pineal gland at night. Since melatonin is produced in the mitochondria of all other cells in a non-circadian manner, the amount synthesized by the pineal gland is less than 5% of the total. Melatonin produced in mitochondria influences glucose metabolism in all cells....

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Veröffentlicht in:	International journal of molecular sciences 2021-11, Vol.22 (22), p.12494
Hauptverfasser:	Reiter, Russel J, Sharma, Ramaswamy, Rosales-Corral, Sergio, Manucha, Walter, Chuffa, Luiz Gustavo de Almeida, Zuccari, Debora Aparecida Pires de Campos
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerobiosis - genetics Animals Bile Cancer Cell Communication - genetics Chloroplasts Circadian rhythms Coenzyme A Cytosol Endocrine system Genotype & phenotype Glucose Glucose - metabolism Glycolysis Glycolysis - genetics Humans Hypoxia Lactic acid Melatonin Melatonin - genetics Melatonin - metabolism Metabolism Mitochondria Mitochondria - metabolism Neoplasms - genetics Neoplasms - metabolism Neoplasms - pathology Oxidative stress Phenotypes Pineal gland Pyruvic acid Retina Review Rhythm Tumors Vertebrates Warburg Effect, Oncologic
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