Retinal optical coherence tomography angiography findings of acute anterior uveitis
Purpose To evaluate the changes in retinal microvasculature in eyes with anterior uveitis (AU) using optical coherence tomography angiography. Methods Foveal avascular zone (FAZ) of superficial capillary plexus (SCP) and deep capillary plexus (DCP), vessel density (VD) of SCP, DCP, and choriocapilla...
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| Veröffentlicht in: | International ophthalmology 2022-05, Vol.42 (5), p.1409-1418 |
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| creator | Yalcinkaya, Gulay Altan, Cigdem Basarir, Berna Cakir, Ihsan |
| description | Purpose
To evaluate the changes in retinal microvasculature in eyes with anterior uveitis (AU) using optical coherence tomography angiography.
Methods
Foveal avascular zone (FAZ) of superficial capillary plexus (SCP) and deep capillary plexus (DCP), vessel density (VD) of SCP, DCP, and choriocapillaris, and central macular thickness (CMT) and central foveal thickness (CFT) were calculated from 34 healthy and 41 uveitic eyes. The parameters were compared between the two groups.
Results
The deep FAZ was significantly smaller in the eyes with AU during the attack than after recovery and the control group (
p
= 0.001 and
p
= 0.003, respectively). The VD in deep capillary plexus (DCP) in eyes with AU during the attack was significantly higher than the control group (
p
= 0.048). The VD in the foveal sector of DCP in eyes with AU during the attack and after recovery was significantly higher than the control group (
p
= 0.001 and
p
= 0.031, respectively). There was no significant difference regarding CMT, CFT, VDs of each segment and each sector, and superficial and deep FAZ between eyes with first uveitis attack and those with recurrent uveitis during the attack and after recovery (
p
> 0.05).
Conclusion
The results of this study show that there is a reduction in the FAZ and an increase in the VD of the DCP of the retina during active AU, and these findings are reversible. Acute AU may affect the macular microvasculature, which is usually temporary, especially in the DCP. |
| doi_str_mv | 10.1007/s10792-021-02129-w |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2604018551</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2667082158</sourcerecordid><originalsourceid>FETCH-LOGICAL-c485t-d023e6a2ab98bb8fb9fd1ce72070375b7c3260cfaa0fdd388aa656a55474efd73</originalsourceid><addsrcrecordid>eNp9kElLBDEQhYMo7n_AgzR48dJaSTqd9FHEDQTB5RzS6coYmemMSbfivzfjuOHBQ1EF9b2X1CNkj8IRBZDHiYJsWAmMLoo15esK2aRC8pLVHFZ_zRtkK6UnAGhkU6-TDV4pLkXDNsndLQ6-N9MizAdvc7fhESP2FoshzMIkmvnjW2H6if-ane87309SEVxh7Dhg3g4YfYjF-IJ-8GmHrDkzTbj72bfJw_nZ_elleX1zcXV6cl3aSomh7IBxrA0zbaPaVrm2cR21KBlIyL9rpeWsBuuMAdd1XCljalEbISpZoesk3yaHS995DM8jpkHPfLI4nZoew5h0VldAlRA0owd_0Kcwxnz3gqolKEaFyhRbUjaGlCI6PY9-ZuKbpqAXketl5DrHrT8i169ZtP9pPbYz7L4lXxlngC-BlFf9BOPP2__YvgOp6o3G</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2667082158</pqid></control><display><type>article</type><title>Retinal optical coherence tomography angiography findings of acute anterior uveitis</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Yalcinkaya, Gulay ; Altan, Cigdem ; Basarir, Berna ; Cakir, Ihsan</creator><creatorcontrib>Yalcinkaya, Gulay ; Altan, Cigdem ; Basarir, Berna ; Cakir, Ihsan</creatorcontrib><description>Purpose
To evaluate the changes in retinal microvasculature in eyes with anterior uveitis (AU) using optical coherence tomography angiography.
Methods
Foveal avascular zone (FAZ) of superficial capillary plexus (SCP) and deep capillary plexus (DCP), vessel density (VD) of SCP, DCP, and choriocapillaris, and central macular thickness (CMT) and central foveal thickness (CFT) were calculated from 34 healthy and 41 uveitic eyes. The parameters were compared between the two groups.
Results
The deep FAZ was significantly smaller in the eyes with AU during the attack than after recovery and the control group (
p
= 0.001 and
p
= 0.003, respectively). The VD in deep capillary plexus (DCP) in eyes with AU during the attack was significantly higher than the control group (
p
= 0.048). The VD in the foveal sector of DCP in eyes with AU during the attack and after recovery was significantly higher than the control group (
p
= 0.001 and
p
= 0.031, respectively). There was no significant difference regarding CMT, CFT, VDs of each segment and each sector, and superficial and deep FAZ between eyes with first uveitis attack and those with recurrent uveitis during the attack and after recovery (
p
> 0.05).
Conclusion
The results of this study show that there is a reduction in the FAZ and an increase in the VD of the DCP of the retina during active AU, and these findings are reversible. Acute AU may affect the macular microvasculature, which is usually temporary, especially in the DCP.</description><identifier>ISSN: 1573-2630</identifier><identifier>ISSN: 0165-5701</identifier><identifier>EISSN: 1573-2630</identifier><identifier>DOI: 10.1007/s10792-021-02129-w</identifier><identifier>PMID: 34837592</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Angiography ; Eye ; Eye (anatomy) ; Fluorescein Angiography - methods ; Humans ; Medical imaging ; Medicine ; Medicine & Public Health ; Microvasculature ; Ophthalmology ; Optical Coherence Tomography ; Original Paper ; Recovery ; Retina ; Retinal Vessels ; Thickness ; Tomography ; Tomography, Optical Coherence - methods ; Uveitis ; Uveitis, Anterior - diagnosis</subject><ispartof>International ophthalmology, 2022-05, Vol.42 (5), p.1409-1418</ispartof><rights>The Author(s), under exclusive licence to Springer Nature B.V. 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer Nature B.V.</rights><rights>The Author(s), under exclusive licence to Springer Nature B.V. 2021.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c485t-d023e6a2ab98bb8fb9fd1ce72070375b7c3260cfaa0fdd388aa656a55474efd73</citedby><cites>FETCH-LOGICAL-c485t-d023e6a2ab98bb8fb9fd1ce72070375b7c3260cfaa0fdd388aa656a55474efd73</cites><orcidid>0000-0001-6248-5902</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10792-021-02129-w$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10792-021-02129-w$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34837592$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yalcinkaya, Gulay</creatorcontrib><creatorcontrib>Altan, Cigdem</creatorcontrib><creatorcontrib>Basarir, Berna</creatorcontrib><creatorcontrib>Cakir, Ihsan</creatorcontrib><title>Retinal optical coherence tomography angiography findings of acute anterior uveitis</title><title>International ophthalmology</title><addtitle>Int Ophthalmol</addtitle><addtitle>Int Ophthalmol</addtitle><description>Purpose
To evaluate the changes in retinal microvasculature in eyes with anterior uveitis (AU) using optical coherence tomography angiography.
Methods
Foveal avascular zone (FAZ) of superficial capillary plexus (SCP) and deep capillary plexus (DCP), vessel density (VD) of SCP, DCP, and choriocapillaris, and central macular thickness (CMT) and central foveal thickness (CFT) were calculated from 34 healthy and 41 uveitic eyes. The parameters were compared between the two groups.
Results
The deep FAZ was significantly smaller in the eyes with AU during the attack than after recovery and the control group (
p
= 0.001 and
p
= 0.003, respectively). The VD in deep capillary plexus (DCP) in eyes with AU during the attack was significantly higher than the control group (
p
= 0.048). The VD in the foveal sector of DCP in eyes with AU during the attack and after recovery was significantly higher than the control group (
p
= 0.001 and
p
= 0.031, respectively). There was no significant difference regarding CMT, CFT, VDs of each segment and each sector, and superficial and deep FAZ between eyes with first uveitis attack and those with recurrent uveitis during the attack and after recovery (
p
> 0.05).
Conclusion
The results of this study show that there is a reduction in the FAZ and an increase in the VD of the DCP of the retina during active AU, and these findings are reversible. Acute AU may affect the macular microvasculature, which is usually temporary, especially in the DCP.</description><subject>Angiography</subject><subject>Eye</subject><subject>Eye (anatomy)</subject><subject>Fluorescein Angiography - methods</subject><subject>Humans</subject><subject>Medical imaging</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Microvasculature</subject><subject>Ophthalmology</subject><subject>Optical Coherence Tomography</subject><subject>Original Paper</subject><subject>Recovery</subject><subject>Retina</subject><subject>Retinal Vessels</subject><subject>Thickness</subject><subject>Tomography</subject><subject>Tomography, Optical Coherence - methods</subject><subject>Uveitis</subject><subject>Uveitis, Anterior - diagnosis</subject><issn>1573-2630</issn><issn>0165-5701</issn><issn>1573-2630</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kElLBDEQhYMo7n_AgzR48dJaSTqd9FHEDQTB5RzS6coYmemMSbfivzfjuOHBQ1EF9b2X1CNkj8IRBZDHiYJsWAmMLoo15esK2aRC8pLVHFZ_zRtkK6UnAGhkU6-TDV4pLkXDNsndLQ6-N9MizAdvc7fhESP2FoshzMIkmvnjW2H6if-ane87309SEVxh7Dhg3g4YfYjF-IJ-8GmHrDkzTbj72bfJw_nZ_elleX1zcXV6cl3aSomh7IBxrA0zbaPaVrm2cR21KBlIyL9rpeWsBuuMAdd1XCljalEbISpZoesk3yaHS995DM8jpkHPfLI4nZoew5h0VldAlRA0owd_0Kcwxnz3gqolKEaFyhRbUjaGlCI6PY9-ZuKbpqAXketl5DrHrT8i169ZtP9pPbYz7L4lXxlngC-BlFf9BOPP2__YvgOp6o3G</recordid><startdate>20220501</startdate><enddate>20220501</enddate><creator>Yalcinkaya, Gulay</creator><creator>Altan, Cigdem</creator><creator>Basarir, Berna</creator><creator>Cakir, Ihsan</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-6248-5902</orcidid></search><sort><creationdate>20220501</creationdate><title>Retinal optical coherence tomography angiography findings of acute anterior uveitis</title><author>Yalcinkaya, Gulay ; Altan, Cigdem ; Basarir, Berna ; Cakir, Ihsan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c485t-d023e6a2ab98bb8fb9fd1ce72070375b7c3260cfaa0fdd388aa656a55474efd73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Angiography</topic><topic>Eye</topic><topic>Eye (anatomy)</topic><topic>Fluorescein Angiography - methods</topic><topic>Humans</topic><topic>Medical imaging</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Microvasculature</topic><topic>Ophthalmology</topic><topic>Optical Coherence Tomography</topic><topic>Original Paper</topic><topic>Recovery</topic><topic>Retina</topic><topic>Retinal Vessels</topic><topic>Thickness</topic><topic>Tomography</topic><topic>Tomography, Optical Coherence - methods</topic><topic>Uveitis</topic><topic>Uveitis, Anterior - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yalcinkaya, Gulay</creatorcontrib><creatorcontrib>Altan, Cigdem</creatorcontrib><creatorcontrib>Basarir, Berna</creatorcontrib><creatorcontrib>Cakir, Ihsan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>International ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yalcinkaya, Gulay</au><au>Altan, Cigdem</au><au>Basarir, Berna</au><au>Cakir, Ihsan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Retinal optical coherence tomography angiography findings of acute anterior uveitis</atitle><jtitle>International ophthalmology</jtitle><stitle>Int Ophthalmol</stitle><addtitle>Int Ophthalmol</addtitle><date>2022-05-01</date><risdate>2022</risdate><volume>42</volume><issue>5</issue><spage>1409</spage><epage>1418</epage><pages>1409-1418</pages><issn>1573-2630</issn><issn>0165-5701</issn><eissn>1573-2630</eissn><abstract>Purpose
To evaluate the changes in retinal microvasculature in eyes with anterior uveitis (AU) using optical coherence tomography angiography.
Methods
Foveal avascular zone (FAZ) of superficial capillary plexus (SCP) and deep capillary plexus (DCP), vessel density (VD) of SCP, DCP, and choriocapillaris, and central macular thickness (CMT) and central foveal thickness (CFT) were calculated from 34 healthy and 41 uveitic eyes. The parameters were compared between the two groups.
Results
The deep FAZ was significantly smaller in the eyes with AU during the attack than after recovery and the control group (
p
= 0.001 and
p
= 0.003, respectively). The VD in deep capillary plexus (DCP) in eyes with AU during the attack was significantly higher than the control group (
p
= 0.048). The VD in the foveal sector of DCP in eyes with AU during the attack and after recovery was significantly higher than the control group (
p
= 0.001 and
p
= 0.031, respectively). There was no significant difference regarding CMT, CFT, VDs of each segment and each sector, and superficial and deep FAZ between eyes with first uveitis attack and those with recurrent uveitis during the attack and after recovery (
p
> 0.05).
Conclusion
The results of this study show that there is a reduction in the FAZ and an increase in the VD of the DCP of the retina during active AU, and these findings are reversible. Acute AU may affect the macular microvasculature, which is usually temporary, especially in the DCP.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>34837592</pmid><doi>10.1007/s10792-021-02129-w</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-6248-5902</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | International ophthalmology, 2022-05, Vol.42 (5), p.1409-1418 |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Angiography Eye Eye (anatomy) Fluorescein Angiography - methods Humans Medical imaging Medicine Medicine & Public Health Microvasculature Ophthalmology Optical Coherence Tomography Original Paper Recovery Retina Retinal Vessels Thickness Tomography Tomography, Optical Coherence - methods Uveitis Uveitis, Anterior - diagnosis |
| title | Retinal optical coherence tomography angiography findings of acute anterior uveitis |
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