Coordination of rigidity modulation and targeting ligand modification on orally-delivered nanoparticles for the treatment of liver fibrosis

Although the individual role of ligand modification or rigidity modulation on oral administration of nanoparticle (NP) has been investigated, how they mutually affect each other remains to be elucidated. Here, we fabricated different rigidity NP with or without surface decoration of FcBP, a neonatal...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of controlled release 2022-01, Vol.341, p.215-226
Hauptverfasser:	Yu, Yinglan, Xing, LiYun, Li, Lian, Wu, Jiawei, He, Jinhan, Huang, Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Epithelial barrier FcBP modification Liver fibrosis Mucus barrier Oral absorption Rigidity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!