Zika virus NS1 suppresses the innate immune responses via miR-146a in human microglial cells

Zika virus (ZIKV) is a positive-single strand RNA virus that belongs to the Flaviviridae family. ZIKV infection causes congenital ZIKV syndrome (CZS) in children and Guillain Barre Syndrome (GBS) in adults. ZIKV infected cells secrete non-structural protein 1 (sNS1), which plays an important role in...

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Veröffentlicht in:	International journal of biological macromolecules 2021-12, Vol.193 (Pt B), p.2290-2296
Hauptverfasser:	Shukla, Astha, Rastogi, Meghana, Singh, Sunit K.
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions - immunology Biochemistry & Molecular Biology Cells, Cultured Chemistry Chemistry, Applied Cytokines - immunology Host immune evasion Human microglial cells Humans Immunity, Innate - immunology Life Sciences & Biomedicine Microglia - immunology Microglia - virology MicroRNAs - immunology miR-146a Physical Sciences Polymer Science RNA, Messenger - immunology Science & Technology Signal Transduction - immunology TNF Receptor-Associated Factor 6 - immunology Up-Regulation - immunology Viral Nonstructural Proteins - immunology Virus Replication - immunology Zika Virus - immunology Zika Virus Infection - immunology Zika Virus Infection - virology Zika virus NS1 protein
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