Urea and Acetamide Rich Solutions Circumvent the Strand Inhibition Problem to Allow Multiple Rounds of DNA and RNA Copying

For decades prebiotic chemists have attempted to achieve replication of RNA under prebiotic conditions with only limited success. One of the long‐recognized impediments to achieving true replication of a duplex (copying of both strands) is the so‐called strand inhibition problem. Specifically, while...

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Veröffentlicht in:Chembiochem : a European journal of chemical biology 2022-01, Vol.23 (1), p.e202100495-n/a
Hauptverfasser: Lozoya‐Colinas, Adriana, Clifton, Bryce E., Grover, Martha A., Hud, Nicholas V.
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Sprache:eng
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