Epithelial mesenchymal transition regulator TWIST1 transcription factor stimulates glucose uptake through upregulation of GLUT1, GLUT3, and GLUT12 in vitro

TWIST1 is a major regulator of epithelial mesenchymal transition process, essential in cancer metastasis. Cancer cells increase glucose uptake capabilities to meet their high energy requirements. In this study, we explored the potential role of TWIST1 on glucose transport into the 293T cells in an i...

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Veröffentlicht in:	In vitro cellular & developmental biology. Animal 2021-12, Vol.57 (10), p.933-943
Hauptverfasser:	Pehlivanoglu, Suray, Sahan, Ozge Burcu, Pehlivanoglu, Sebnem, Kont, Kadriye Aktas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics Biomedical and Life Sciences BIOTECHNOLOGY Cancer Cell Biology Cell Culture Developmental Biology Ectopic expression Electroporation Energy requirements Evaluation Fetal calf serum Genes Glucose Glucose transport Insulin Insulin receptor substrate 1 Life Sciences Mesenchyme Metastases Molecular modelling Receptors Stem Cells Stimulation Substrates Tumorigenesis
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