Opuntia ficus-indica Extract and Isorhamnetin-3-O-Glucosyl-Rhamnoside Diminish Tumor Growth of Colon Cancer Cells Xenografted in Immune-Suppressed Mice through the Activation of Apoptosis Intrinsic Pathway

This study aimed to evaluate the effects of Opuntia ficus-indica extract (OFI-E) and its glycoside isorhamnetin-3- O -glucosyl-rhamnoside (IGR) on the growth of human colorectal adenocarcinoma cells and in a xenografted-immunosuppressed mice model. The IC 50 values of OFI-E and IGR on colon cancer c...

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Veröffentlicht in:	Plant foods for human nutrition (Dordrecht) 2021-12, Vol.76 (4), p.434-441
Hauptverfasser:	Antunes-Ricardo, M., Guardado-Félix, D., Rocha-Pizaña, M. R., Garza-Martínez, J., Acevedo-Pacheco, L., Gutiérrez-Uribe, J. A., Villela-Castrejón, J., López-Pacheco, F., Serna-Saldívar, S. O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Animals Apoptosis Bcl-2 protein Caspase-9 Cell cycle Chemistry Chemistry and Materials Science Chemistry/Food Science Cholesterol Colon Colon cancer Colonic Neoplasms - drug therapy Colorectal cancer Colorectal carcinoma Ecology Food Science Histone Deacetylases Humans Mice Nutrition Opuntia Opuntia ficus-indica Original Paper Peroxidase Plant Extracts - pharmacology Plant Physiology Quercetin - analogs & derivatives Tumors
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