High-throughput Antiviral Assays to Screen for Inhibitors of Zika Virus Replication

Antiviral drug discovery requires the development of reliable biochemical and cellular assays that can be performed in high-throughput screening (HTS) formats. The flavivirus non-structural (NS) proteins are thought to co-translationally assemble on the endoplasmic reticulum (ER) membranes, forming...

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Veröffentlicht in:	Journal of Visualized Experiments 2021-10 (176)
Hauptverfasser:	Fernandes, Rafaela S., Noske, Gabriela D., Gawriljuk, Victor O., de Oliveira, Ketllyn I. Z., Godoy, Andre S., Mesquita, Nathalya C. M. R., Oliva, Glaucius
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Agents - metabolism High-Throughput Screening Assays Immunology and Infection Mammals Virus Replication Zika Virus - genetics Zika Virus Infection - drug therapy
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