Extract of Moutan radicis cortex and Cinnamomi ramulus ameliorates laser-induced choroidal neovascularization in Brown-Norway rats

•MRCCR is 50% ethanol extract of Moutan radicis cortex and Cinnamomi ramulus (1:1).•Oral MRCCR significantly reduced the choroidal neovascularization by laser injury.•Oral MRCCR significantly reduced the extent of fluorescein leakage by laser injury.•Combining oral MRCCR and intraocular injecting an...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2022-01, Vol.94, p.153794-153794, Article 153794
Hauptverfasser:	Lee, Ik Soo, Kim, Chan-Sik, Kim, Junghyun, Jo, Kyuhyung, Hyun, Soo Wang, Zhang, Haiying, Noh, MinYoung, Kwon, Young-Guen, Kim, MyungHwa, Kim, Jin Sook
Format:	Artikel
Sprache:	eng
Schlagworte:	50% Ethanol extract of Moutan radicis cortex and Cinnamomi ramulus Animals Anti-angiogenic action Choroidal neovascularization Choroidal Neovascularization - drug therapy Disease Models, Animal Endothelial Cells Fluorescein Angiography Humans Lasers Plant Extracts - pharmacology Rats Rats, Inbred BN Vascular Endothelial Growth Factor A
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