Antimicrobial and Anticancer Application of Silver(I) Dipeptide Complexes

Three silver(I) dipeptide complexes [Ag(GlyGly)] (NO ) (AgGlyGly), [Ag (GlyAla)(NO ) ] (AgGlyAla) and [Ag (HGlyAsp)(NO )] (AgGlyAsp) were prepared, investigated and characterized by vibrational spectroscopy (mid-IR), elemental and thermogravimetric analysis and mass spectrometry. For AgGlyGly, X-ray...

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Veröffentlicht in:	Molecules (Basel, Switzerland) Switzerland), 2021-10, Vol.26 (21), p.6335
Hauptverfasser:	Kuzderová, Gabriela, Rendošová, Michaela, Gyepes, Róbert, Sovová, Simona, Sabolová, Danica, Vilková, Mária, Olejníková, Petra, Bačová, Ivana, Stokič, Simonida, Kello, Martin, Vargová, Zuzana
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Anti-Infective Agents - chemical synthesis Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology anticancer activity Antiinfectives and antibacterials Antimicrobial activity Antimicrobial agents Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Cancer Cell cycle Cell Cycle - drug effects Cell Line, Tumor Chemical Phenomena Chemistry Techniques, Synthetic Colorimetry Coordination Complexes - chemical synthesis Coordination Complexes - chemistry Coordination Complexes - pharmacology COVID-19 crystal structure Crystallography Crystallography, X-Ray Cytotoxicity Deoxyribonucleic acid dipeptide Dipeptides - chemistry DNA DNA topoisomerase Dose-Response Relationship, Drug Drug Stability E coli Humans Immune system Infrared analysis Infrared spectroscopy Ligands Mass spectrometry Mass spectroscopy Microorganisms Molecular Conformation Molecular Dynamics Simulation NMR Nuclear magnetic resonance Organisms Pandemics Pathogens Peptides Selectivity Silver Silver - chemistry silver(I) complexes Spectrum Analysis stability Structure-Activity Relationship Thermogravimetric analysis Thermogravimetry X-ray crystallography
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