The gene regulation knowledge commons: the action area of GREEKC
As computational modeling becomes more essential to analyze and understand biological regulatory mechanisms, governance of the many databases and knowledge bases that support this domain is crucial to guarantee reliability and interoperability of resources. To address this, the COST Action Gene Regu...
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Veröffentlicht in: | Biochimica et biophysica acta. Gene regulatory mechanisms 2022-01, Vol.1865 (1), p.194768-194768, Article 194768 |
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container_title | Biochimica et biophysica acta. Gene regulatory mechanisms |
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creator | Kuiper, Martin Bonello, Joseph Fernández-Breis, Jesualdo T. Bucher, Philipp Futschik, Matthias E. Gaudet, Pascale Kulakovskiy, Ivan V. Licata, Luana Logie, Colin Lovering, Ruth C. Makeev, Vsevolod J. Orchard, Sandra Panni, Simona Perfetto, Livia Sant, David Schulz, Stefan Vercruysse, Steven Zerbino, Daniel R. Lægreid, Astrid |
description | As computational modeling becomes more essential to analyze and understand biological regulatory mechanisms, governance of the many databases and knowledge bases that support this domain is crucial to guarantee reliability and interoperability of resources. To address this, the COST Action Gene Regulation Ensemble Effort for the Knowledge Commons (GREEKC, CA15205, www.greekc.org) organized nine workshops in a four-year period, starting September 2016. The workshops brought together a wide range of experts from all over the world working on various steps in the knowledge management process that focuses on understanding gene regulatory mechanisms. The discussions between ontologists, curators, text miners, biologists, bioinformaticians, philosophers and computational scientists spawned a host of activities aimed to standardize and update existing knowledge management workflows and involve end-users in the process of designing the Gene Regulation Knowledge Commons (GRKC). Here the GREEKC consortium describes its main achievements in improving this GRKC. |
doi_str_mv | 10.1016/j.bbagrm.2021.194768 |
format | Article |
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subjects | Biocuration Computational biology Knowledge Commons Ontologies Text mining Web services |
title | The gene regulation knowledge commons: the action area of GREEKC |
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