C1r Upregulates Production of Matrix Metalloproteinase-13 and Promotes Invasion of Cutaneous Squamous Cell Carcinoma

Cutaneous squamous cell carcinoma (cSCC) is the most common metastatic skin cancer, with increasing incidence worldwide. Previous studies have shown the role of the complement system in cSCC progression. In this study, we have investigated the mechanistic role of serine proteinase C1r, a component o...

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Veröffentlicht in:	Journal of investigative dermatology 2022-05, Vol.142 (5), p.1478-1488.e9
Hauptverfasser:	Viiklepp, Kristina, Nissinen, Liisa, Ojalill, Marjaana, Riihilä, Pilvi, Kallajoki, Markku, Meri, Seppo, Heino, Jyrki, Kähäri, Veli-Matti
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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