Peripherally administered persistent organic pollutants distribute to the brain of developing chicken embryo in concentrations relevant for human exposure

•A human relevant POP mixture was injected into the allantois of the chicken egg.•Different POPs reached the chicken embryo brain at varying speed and concentrations.•Brain concentrations were in the same range as measured in humans.•Measured concentrations could be fitted to specific pharmacokineti...

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Veröffentlicht in:Neurotoxicology (Park Forest South) 2022-01, Vol.88, p.79-87
Hauptverfasser: Yadav, Ajay, Verhaegen, Steven, Hadera, Mussie Ghezu, Berntsen, Hanne Friis, Berg, Vidar, Lyche, Jan Ludvig, Sabaredzovic, Azemira, Haug, Line Småstuen, Myhre, Oddvar, Zimmer, Karin Elisabeth, Paulsen, Ragnhild Elisabeth, Ropstad, Erik, Boix, Fernando
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Sprache:eng
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