A low dose of bisphenol A stimulates estradiol production by regulating β-catenin-FOXL2-CYP19A1 pathway in human ovarian granulosa cells

Bisphenol A (BPA) is a well-known endocrine-disrupting chemical that interferes with normal steroid hormone production in various species. However, the underlying mechanism of the effect of BPA on steroid production in the human ovary is not well understood. In the present study, we found that BPA,...

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Veröffentlicht in:	Biochemical and biophysical research communications 2021-12, Vol.583, p.192-198
Hauptverfasser:	Liu, Haifeng, Jin, Hanyong, Kim, Guenhwi, Bae, Jeehyeon
Format:	Artikel
Sprache:	eng
Schlagworte:	Biphasic effect Estradiol FOXL2 Ovary Steroidogenesis β-catenin
Online-Zugang:	Volltext
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