A novel in vitro approach to investigate the effect of food intake on release profile of valsartan in solid dispersion-floating gel in-situ delivery system

•Valsartan was formulated into solid dispersion which was incorporated into floating gel in-situ delivery system.•The formulations showed desirable characteristics and sustained release profiles.•The food intake did not affect the in vitro release of valsartan after 2 h in an empty gastric environme...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2022-01, Vol.168, p.106057-106057, Article 106057
Hauptverfasser:	Himawan, Achmad, Djide, Nana Juniarti Natsir, Mardikasari, Sandra Aulia, Utami, Rifka Nurul, Arjuna, Andi, Donnelly, Ryan.F., Permana, Andi Dian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Availability Controlled release Delayed-Action Preparations Eating Floating gel in situ system Gels Solid dispersion Solubility Tablets Valsartan
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