Single-Cell Analysis Reveals EP4 as a Target for Restoring T-Cell Infiltration and Sensitizing Prostate Cancer to Immunotherapy

Immunotherapies targeting immune checkpoint molecules have shown promising treatment for a subset of cancers; however, many "cold" tumors, such as prostate cancer, remain unresponsive. We aimed to identify a potential targetable marker relevant to prostate cancer and develop novel immunoth...

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Veröffentlicht in:	Clinical cancer research 2022-02, Vol.28 (3), p.552-567
Hauptverfasser:	Peng, Shihong, Hu, Pan, Xiao, Yu-Tian, Lu, Weiqiang, Guo, Dandan, Hu, Shixiu, Xie, Jiayi, Wang, Minna, Yu, Weiwei, Yang, Junjie, Chen, Huang, Zhang, Xiaomin, Zhu, Yasheng, Wang, Ye, Yang, Yue, Zhu, Guanghui, Chen, Sujun, Wang, Jian, Zhang, Bo, Chen, Weidong, Wu, Huangan, Sun, Zhenliang, Ding, Tao, Zhang, Hankun, Yi, Zhengfang, Liu, Mingyao, Ren, Shancheng
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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