Alpha-terpineol prevents myocardial damage against isoproterenol-MI induced in Wistar-Kyoto rats: new possible to promote cardiovascular integrity

Alpha-terpineol (TPN) is one of the major components of the resin obtained from Protium heptaphyllum. This plant has been utilized as medicine by Brazilian indigenous tribes to treat cardiovascular diseases. Scientific reports have shown that the TPN possesses vasorelaxant and antihypertensive effec...

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Veröffentlicht in:	Life sciences (1973) 2022-02, Vol.290, p.120087-120087, Article 120087
Hauptverfasser:	Paulino, Emanuel Tenório, Rodrigues, Amanda Karine Barros Ferreira, Machado, Maria Luiza Dal Pont, de Oliveira, Kelly Rayane Vital, Bernardino, Alessando César, Quintans-Júnior, Lucindo José, Oliveira, Aldeídia Pereira, Ribeiro, Êurica Adélia Nogueira
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-terpineol Animals Antihypertensives Antioxidants - pharmacology Baroreceptors Biomarkers - metabolism Cardioprotection Cardiotonic Agents - pharmacology Cardiotoxicity Cardiotoxicity - drug therapy Cardiotoxicity - metabolism Cardiovascular diseases Cardiovascular Diseases - drug therapy Cyclohexane Monoterpenes - metabolism Cyclohexane Monoterpenes - pharmacology Damage prevention Edema EKG Heart - drug effects Hemodynamics Hemodynamics - drug effects Hemorrhage Hypertrophy Inflammation Isoproterenol Isoproterenol - pharmacology Lipid Peroxidation - drug effects Lymphocytes Male Medicinal plants Myocardial infarction Myocardial Infarction - pathology Myocardium Myocardium - metabolism Necrosis Oral administration Protium heptaphyllum Rats Rats, Inbred WKY Reflexes Rodents Tachycardia Terpineol Wistar-Kyoto rats
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