Common ocular findings in patients with acne rosacea
Purpose To evaluate ocular surface manifestations in patients with acne rosecea (AR) and to find out main features indicating a propensity toward an association with disease diagnosis. Methods Right eyes of consecutive 76 AR patients and 113 age-gender matched healthy subjects were enrolled. Ophthal...
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| Veröffentlicht in: | International ophthalmology 2022-04, Vol.42 (4), p.1077-1084 |
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| creator | Ozturk, Taylan Kayabasi, Mustafa Ozbagcivan, Ozlem Ayhan, Ziya Utine, Canan Asli |
| description | Purpose
To evaluate ocular surface manifestations in patients with acne rosecea (AR) and to find out main features indicating a propensity toward an association with disease diagnosis.
Methods
Right eyes of consecutive 76 AR patients and 113 age-gender matched healthy subjects were enrolled. Ophthalmologic examinations including tear break-up time (t-BUT) and Schirmer-2 tests to analyze tear film insufficiency, optical coherence tomography (OCT)-assisted infrared meibography to analyze meibomian gland drop-out, and Ocular Surface Disease Index (OSDI) questionnaire were performed in all participants.
Results
No statistically differences were found in visual acuity, intraocular pressure, central corneal thickness, and axial length assessments between the study and control eyes. Study eyes had more foreign body sensation, itching, dryness, hyperemia, conjunctival telangiectasia, and meibomitis (
p
≤ 0.005, for all). Significantly higher t-BUT and Schirmer-2 tests; lower-eyelid and total OCT meibography; and OSDI scores were found in AR patients (
p
|
| doi_str_mv | 10.1007/s10792-021-02093-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2593043244</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2648325400</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-c6a48b281260d2384c42596029f848403aae2c042ebf70ce696e6a91dcf186363</originalsourceid><addsrcrecordid>eNp9kE1LxDAQhoMorq7-AQ9S8OKlOpmkSXOUxS9Y8KLnkE3Ttcs2XZMW8d8b7fqBBw9hAvPMm8xDyAmFCwogLyMFqTAHpOmAYnmxQw5oIVmOgsHur_uEHMa4AgAlldgnE8YlytQ4IHzWtW3ns84OaxOyuvFV45cxa3y2MX3jfB-z16Z_zoz1LgtdNNaZI7JXm3V0x9s6JU8314-zu3z-cHs_u5rnlsmiz60wvFxgSVFAhazklmOhBKCqS15yYMY4tMDRLWoJ1gklnDCKVrampWCCTcn5mLsJ3cvgYq_bJlq3XhvvuiHqlMaAM-Q8oWd_0FU3BJ9-p1HwkmHBARKFI2XTJjG4Wm9C05rwpinoD6d6dKqTU_3pVBdp6HQbPSxaV32PfElMABuBmFp-6cLP2__EvgOPDH7S</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2648325400</pqid></control><display><type>article</type><title>Common ocular findings in patients with acne rosacea</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Ozturk, Taylan ; Kayabasi, Mustafa ; Ozbagcivan, Ozlem ; Ayhan, Ziya ; Utine, Canan Asli</creator><creatorcontrib>Ozturk, Taylan ; Kayabasi, Mustafa ; Ozbagcivan, Ozlem ; Ayhan, Ziya ; Utine, Canan Asli</creatorcontrib><description>Purpose
To evaluate ocular surface manifestations in patients with acne rosecea (AR) and to find out main features indicating a propensity toward an association with disease diagnosis.
Methods
Right eyes of consecutive 76 AR patients and 113 age-gender matched healthy subjects were enrolled. Ophthalmologic examinations including tear break-up time (t-BUT) and Schirmer-2 tests to analyze tear film insufficiency, optical coherence tomography (OCT)-assisted infrared meibography to analyze meibomian gland drop-out, and Ocular Surface Disease Index (OSDI) questionnaire were performed in all participants.
Results
No statistically differences were found in visual acuity, intraocular pressure, central corneal thickness, and axial length assessments between the study and control eyes. Study eyes had more foreign body sensation, itching, dryness, hyperemia, conjunctival telangiectasia, and meibomitis (
p
≤ 0.005, for all). Significantly higher t-BUT and Schirmer-2 tests; lower-eyelid and total OCT meibography; and OSDI scores were found in AR patients (
p
< 0.05, for all). Among all, only conjunctival telangiectasia (
p
= 0.001; OR:0.070, 95% CI:0.015–0.330) was found to be major independent predictor for AR diagnosis.
Conclusion
Detailed slit-lamp examination to detect any conjunctival telangiectasia seems to be crucial in recalcitrant dry eye cases, not to miss underlying AR. Especially, lower-eyelid OCT meibography score may be sensitively used for disease staging.</description><identifier>ISSN: 1573-2630</identifier><identifier>ISSN: 0165-5701</identifier><identifier>EISSN: 1573-2630</identifier><identifier>DOI: 10.1007/s10792-021-02093-5</identifier><identifier>PMID: 34727263</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Acne ; Acuity ; Cornea ; Diagnosis ; Dry Eye Syndromes - complications ; Dry Eye Syndromes - etiology ; Eye (anatomy) ; Eyelid ; Eyelid Diseases - diagnosis ; Humans ; Hyperemia ; Infrared analysis ; Intraocular pressure ; Itching ; Medicine ; Medicine & Public Health ; Meibomian Glands - diagnostic imaging ; Ophthalmology ; Optical Coherence Tomography ; Original Paper ; Pruritus ; Rosacea ; Rosacea - complications ; Rosacea - diagnosis ; Sensation ; Skin diseases ; Tears ; Telangiectasis ; Visual acuity</subject><ispartof>International ophthalmology, 2022-04, Vol.42 (4), p.1077-1084</ispartof><rights>The Author(s), under exclusive licence to Springer Nature B.V. 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer Nature B.V.</rights><rights>The Author(s), under exclusive licence to Springer Nature B.V. 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-c6a48b281260d2384c42596029f848403aae2c042ebf70ce696e6a91dcf186363</citedby><cites>FETCH-LOGICAL-c375t-c6a48b281260d2384c42596029f848403aae2c042ebf70ce696e6a91dcf186363</cites><orcidid>0000-0001-6633-0553</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10792-021-02093-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10792-021-02093-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34727263$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ozturk, Taylan</creatorcontrib><creatorcontrib>Kayabasi, Mustafa</creatorcontrib><creatorcontrib>Ozbagcivan, Ozlem</creatorcontrib><creatorcontrib>Ayhan, Ziya</creatorcontrib><creatorcontrib>Utine, Canan Asli</creatorcontrib><title>Common ocular findings in patients with acne rosacea</title><title>International ophthalmology</title><addtitle>Int Ophthalmol</addtitle><addtitle>Int Ophthalmol</addtitle><description>Purpose
To evaluate ocular surface manifestations in patients with acne rosecea (AR) and to find out main features indicating a propensity toward an association with disease diagnosis.
Methods
Right eyes of consecutive 76 AR patients and 113 age-gender matched healthy subjects were enrolled. Ophthalmologic examinations including tear break-up time (t-BUT) and Schirmer-2 tests to analyze tear film insufficiency, optical coherence tomography (OCT)-assisted infrared meibography to analyze meibomian gland drop-out, and Ocular Surface Disease Index (OSDI) questionnaire were performed in all participants.
Results
No statistically differences were found in visual acuity, intraocular pressure, central corneal thickness, and axial length assessments between the study and control eyes. Study eyes had more foreign body sensation, itching, dryness, hyperemia, conjunctival telangiectasia, and meibomitis (
p
≤ 0.005, for all). Significantly higher t-BUT and Schirmer-2 tests; lower-eyelid and total OCT meibography; and OSDI scores were found in AR patients (
p
< 0.05, for all). Among all, only conjunctival telangiectasia (
p
= 0.001; OR:0.070, 95% CI:0.015–0.330) was found to be major independent predictor for AR diagnosis.
Conclusion
Detailed slit-lamp examination to detect any conjunctival telangiectasia seems to be crucial in recalcitrant dry eye cases, not to miss underlying AR. Especially, lower-eyelid OCT meibography score may be sensitively used for disease staging.</description><subject>Acne</subject><subject>Acuity</subject><subject>Cornea</subject><subject>Diagnosis</subject><subject>Dry Eye Syndromes - complications</subject><subject>Dry Eye Syndromes - etiology</subject><subject>Eye (anatomy)</subject><subject>Eyelid</subject><subject>Eyelid Diseases - diagnosis</subject><subject>Humans</subject><subject>Hyperemia</subject><subject>Infrared analysis</subject><subject>Intraocular pressure</subject><subject>Itching</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Meibomian Glands - diagnostic imaging</subject><subject>Ophthalmology</subject><subject>Optical Coherence Tomography</subject><subject>Original Paper</subject><subject>Pruritus</subject><subject>Rosacea</subject><subject>Rosacea - complications</subject><subject>Rosacea - diagnosis</subject><subject>Sensation</subject><subject>Skin diseases</subject><subject>Tears</subject><subject>Telangiectasis</subject><subject>Visual acuity</subject><issn>1573-2630</issn><issn>0165-5701</issn><issn>1573-2630</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kE1LxDAQhoMorq7-AQ9S8OKlOpmkSXOUxS9Y8KLnkE3Ttcs2XZMW8d8b7fqBBw9hAvPMm8xDyAmFCwogLyMFqTAHpOmAYnmxQw5oIVmOgsHur_uEHMa4AgAlldgnE8YlytQ4IHzWtW3ns84OaxOyuvFV45cxa3y2MX3jfB-z16Z_zoz1LgtdNNaZI7JXm3V0x9s6JU8314-zu3z-cHs_u5rnlsmiz60wvFxgSVFAhazklmOhBKCqS15yYMY4tMDRLWoJ1gklnDCKVrampWCCTcn5mLsJ3cvgYq_bJlq3XhvvuiHqlMaAM-Q8oWd_0FU3BJ9-p1HwkmHBARKFI2XTJjG4Wm9C05rwpinoD6d6dKqTU_3pVBdp6HQbPSxaV32PfElMABuBmFp-6cLP2__EvgOPDH7S</recordid><startdate>20220401</startdate><enddate>20220401</enddate><creator>Ozturk, Taylan</creator><creator>Kayabasi, Mustafa</creator><creator>Ozbagcivan, Ozlem</creator><creator>Ayhan, Ziya</creator><creator>Utine, Canan Asli</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-6633-0553</orcidid></search><sort><creationdate>20220401</creationdate><title>Common ocular findings in patients with acne rosacea</title><author>Ozturk, Taylan ; Kayabasi, Mustafa ; Ozbagcivan, Ozlem ; Ayhan, Ziya ; Utine, Canan Asli</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-c6a48b281260d2384c42596029f848403aae2c042ebf70ce696e6a91dcf186363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acne</topic><topic>Acuity</topic><topic>Cornea</topic><topic>Diagnosis</topic><topic>Dry Eye Syndromes - complications</topic><topic>Dry Eye Syndromes - etiology</topic><topic>Eye (anatomy)</topic><topic>Eyelid</topic><topic>Eyelid Diseases - diagnosis</topic><topic>Humans</topic><topic>Hyperemia</topic><topic>Infrared analysis</topic><topic>Intraocular pressure</topic><topic>Itching</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Meibomian Glands - diagnostic imaging</topic><topic>Ophthalmology</topic><topic>Optical Coherence Tomography</topic><topic>Original Paper</topic><topic>Pruritus</topic><topic>Rosacea</topic><topic>Rosacea - complications</topic><topic>Rosacea - diagnosis</topic><topic>Sensation</topic><topic>Skin diseases</topic><topic>Tears</topic><topic>Telangiectasis</topic><topic>Visual acuity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ozturk, Taylan</creatorcontrib><creatorcontrib>Kayabasi, Mustafa</creatorcontrib><creatorcontrib>Ozbagcivan, Ozlem</creatorcontrib><creatorcontrib>Ayhan, Ziya</creatorcontrib><creatorcontrib>Utine, Canan Asli</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>International ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ozturk, Taylan</au><au>Kayabasi, Mustafa</au><au>Ozbagcivan, Ozlem</au><au>Ayhan, Ziya</au><au>Utine, Canan Asli</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Common ocular findings in patients with acne rosacea</atitle><jtitle>International ophthalmology</jtitle><stitle>Int Ophthalmol</stitle><addtitle>Int Ophthalmol</addtitle><date>2022-04-01</date><risdate>2022</risdate><volume>42</volume><issue>4</issue><spage>1077</spage><epage>1084</epage><pages>1077-1084</pages><issn>1573-2630</issn><issn>0165-5701</issn><eissn>1573-2630</eissn><abstract>Purpose
To evaluate ocular surface manifestations in patients with acne rosecea (AR) and to find out main features indicating a propensity toward an association with disease diagnosis.
Methods
Right eyes of consecutive 76 AR patients and 113 age-gender matched healthy subjects were enrolled. Ophthalmologic examinations including tear break-up time (t-BUT) and Schirmer-2 tests to analyze tear film insufficiency, optical coherence tomography (OCT)-assisted infrared meibography to analyze meibomian gland drop-out, and Ocular Surface Disease Index (OSDI) questionnaire were performed in all participants.
Results
No statistically differences were found in visual acuity, intraocular pressure, central corneal thickness, and axial length assessments between the study and control eyes. Study eyes had more foreign body sensation, itching, dryness, hyperemia, conjunctival telangiectasia, and meibomitis (
p
≤ 0.005, for all). Significantly higher t-BUT and Schirmer-2 tests; lower-eyelid and total OCT meibography; and OSDI scores were found in AR patients (
p
< 0.05, for all). Among all, only conjunctival telangiectasia (
p
= 0.001; OR:0.070, 95% CI:0.015–0.330) was found to be major independent predictor for AR diagnosis.
Conclusion
Detailed slit-lamp examination to detect any conjunctival telangiectasia seems to be crucial in recalcitrant dry eye cases, not to miss underlying AR. Especially, lower-eyelid OCT meibography score may be sensitively used for disease staging.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>34727263</pmid><doi>10.1007/s10792-021-02093-5</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-6633-0553</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1573-2630 |
| ispartof | International ophthalmology, 2022-04, Vol.42 (4), p.1077-1084 |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Acne Acuity Cornea Diagnosis Dry Eye Syndromes - complications Dry Eye Syndromes - etiology Eye (anatomy) Eyelid Eyelid Diseases - diagnosis Humans Hyperemia Infrared analysis Intraocular pressure Itching Medicine Medicine & Public Health Meibomian Glands - diagnostic imaging Ophthalmology Optical Coherence Tomography Original Paper Pruritus Rosacea Rosacea - complications Rosacea - diagnosis Sensation Skin diseases Tears Telangiectasis Visual acuity |
| title | Common ocular findings in patients with acne rosacea |
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