FtsK and SpoIIIE, coordinators of chromosome segregation and envelope remodeling in bacteria
The translocation of DNA during bacterial cytokinesis is mediated by the SpoIIIE/FtsK family of proteins. These proteins ensure efficient chromosome segregation into sister cells by ATP-driven translocation of DNA and they control chromosome dimer resolution. How FtsK/SpoIIIE mediate chromosome tran...
Gespeichert in:
| Veröffentlicht in: | Trends in microbiology (Regular ed.) 2022-05, Vol.30 (5), p.480-494 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 494 |
|---|---|
| container_issue | 5 |
| container_start_page | 480 |
| container_title | Trends in microbiology (Regular ed.) |
| container_volume | 30 |
| creator | Chan, Helena Mohamed, Ahmed M.T. Grainge, Ian Rodrigues, Christopher D.A. |
| description | The translocation of DNA during bacterial cytokinesis is mediated by the SpoIIIE/FtsK family of proteins. These proteins ensure efficient chromosome segregation into sister cells by ATP-driven translocation of DNA and they control chromosome dimer resolution. How FtsK/SpoIIIE mediate chromosome translocation during cytokinesis in Gram-positive and Gram-negative organisms has been the subject of debate. Studies on FtsK in Escherichia coli, and recent work on SpoIIIE in Bacillus subtilis, have identified interactions between each translocase and the division machinery, supporting the idea that SpoIIIE and FtsK coordinate the final steps of cytokinesis with completion of chromosome segregation. Here we summarize and discuss the view that SpoIIIE and FtsK play similar roles in coordinating cytokinesis with chromosome segregation, during growth and differentiation.
A recent study shows that SpoIIIE interacts with proteins that are connected to the cell envelope during spore development.FtsK appears to interact with proteins within all layers of the Gram-negative cell envelope.SpoIIIE and FtsK are both multifunctional and they coordinate cell-envelope remodeling with chromosome segregation.Both SpoIIIE and FtsK likely regulate peptidoglycan remodeling at the septum.Advances in cryo-electron microscopy may reveal how FtsK and SpoIIIE complexes are organized during cytokinesis. |
| doi_str_mv | 10.1016/j.tim.2021.10.002 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2593027670</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0966842X21002420</els_id><sourcerecordid>2667262384</sourcerecordid><originalsourceid>FETCH-LOGICAL-c424t-6f740e50a65cc5f3a0606ae94ea7b74b89d82eb1bc64c05bda853364a3df93fd3</originalsourceid><addsrcrecordid>eNp9kE2LFDEQhoMo7uzqD_AiAS8e7LHy2d14WpbddXDBgwoehJBOqscM3cmY9Cz47804qwcPnooqnveleAh5wWDNgOm3u_US5jUHzuq-BuCPyIp1bddI0cFjsoJe66aT_OsZOS9lBwBKcfWUnAnZ8o5xvSLfbpbygdro6ad92mw212-oSyn7EO2ScqFppO57TnMqaUZacJtxa5eQ4u8Mxnuc0h5pxjl5nELc0hDpYN2COdhn5Mlop4LPH-YF-XJz_fnqfXP38XZzdXnXOMnl0uixlYAKrFbOqVFY0KAt9hJtO7Ry6HrfcRzY4LR0oAZvOyWEllb4sRejFxfk9al3n9OPA5bFzKE4nCYbMR2K4aoXwFvdQkVf_YPu0iHH-p3hWrdcc9HJSrET5XIqJeNo9jnMNv80DMxRvdmZqt4c1R9PVX3NvHxoPgwz-r-JP64r8O4EYFVxHzCb4gJGhz5kdIvxKfyn_hdDWZP7</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2667262384</pqid></control><display><type>article</type><title>FtsK and SpoIIIE, coordinators of chromosome segregation and envelope remodeling in bacteria</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Chan, Helena ; Mohamed, Ahmed M.T. ; Grainge, Ian ; Rodrigues, Christopher D.A.</creator><creatorcontrib>Chan, Helena ; Mohamed, Ahmed M.T. ; Grainge, Ian ; Rodrigues, Christopher D.A.</creatorcontrib><description>The translocation of DNA during bacterial cytokinesis is mediated by the SpoIIIE/FtsK family of proteins. These proteins ensure efficient chromosome segregation into sister cells by ATP-driven translocation of DNA and they control chromosome dimer resolution. How FtsK/SpoIIIE mediate chromosome translocation during cytokinesis in Gram-positive and Gram-negative organisms has been the subject of debate. Studies on FtsK in Escherichia coli, and recent work on SpoIIIE in Bacillus subtilis, have identified interactions between each translocase and the division machinery, supporting the idea that SpoIIIE and FtsK coordinate the final steps of cytokinesis with completion of chromosome segregation. Here we summarize and discuss the view that SpoIIIE and FtsK play similar roles in coordinating cytokinesis with chromosome segregation, during growth and differentiation.
A recent study shows that SpoIIIE interacts with proteins that are connected to the cell envelope during spore development.FtsK appears to interact with proteins within all layers of the Gram-negative cell envelope.SpoIIIE and FtsK are both multifunctional and they coordinate cell-envelope remodeling with chromosome segregation.Both SpoIIIE and FtsK likely regulate peptidoglycan remodeling at the septum.Advances in cryo-electron microscopy may reveal how FtsK and SpoIIIE complexes are organized during cytokinesis.</description><identifier>ISSN: 0966-842X</identifier><identifier>EISSN: 1878-4380</identifier><identifier>DOI: 10.1016/j.tim.2021.10.002</identifier><identifier>PMID: 34728126</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Bacillus subtilis - genetics ; Bacillus subtilis - metabolism ; Bacterial Proteins - genetics ; Bacterial Proteins - metabolism ; cell envelope ; Chromatin remodeling ; Chromosome Segregation ; Chromosome translocations ; Chromosomes ; Chromosomes, Bacterial - genetics ; Chromosomes, Bacterial - metabolism ; Cytokinesis ; Deoxyribonucleic acid ; DNA ; DNA - metabolism ; DNA translocases ; DNA, Bacterial - metabolism ; E coli ; Escherichia coli - genetics ; Escherichia coli - metabolism ; Escherichia coli Proteins - genetics ; FtsK ; Membrane Proteins - metabolism ; Proteins ; SpoIIIE ; Translocase ; Translocation</subject><ispartof>Trends in microbiology (Regular ed.), 2022-05, Vol.30 (5), p.480-494</ispartof><rights>2021 Elsevier Ltd</rights><rights>Copyright © 2021 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Science Ltd. May 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c424t-6f740e50a65cc5f3a0606ae94ea7b74b89d82eb1bc64c05bda853364a3df93fd3</citedby><cites>FETCH-LOGICAL-c424t-6f740e50a65cc5f3a0606ae94ea7b74b89d82eb1bc64c05bda853364a3df93fd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0966842X21002420$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34728126$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chan, Helena</creatorcontrib><creatorcontrib>Mohamed, Ahmed M.T.</creatorcontrib><creatorcontrib>Grainge, Ian</creatorcontrib><creatorcontrib>Rodrigues, Christopher D.A.</creatorcontrib><title>FtsK and SpoIIIE, coordinators of chromosome segregation and envelope remodeling in bacteria</title><title>Trends in microbiology (Regular ed.)</title><addtitle>Trends Microbiol</addtitle><description>The translocation of DNA during bacterial cytokinesis is mediated by the SpoIIIE/FtsK family of proteins. These proteins ensure efficient chromosome segregation into sister cells by ATP-driven translocation of DNA and they control chromosome dimer resolution. How FtsK/SpoIIIE mediate chromosome translocation during cytokinesis in Gram-positive and Gram-negative organisms has been the subject of debate. Studies on FtsK in Escherichia coli, and recent work on SpoIIIE in Bacillus subtilis, have identified interactions between each translocase and the division machinery, supporting the idea that SpoIIIE and FtsK coordinate the final steps of cytokinesis with completion of chromosome segregation. Here we summarize and discuss the view that SpoIIIE and FtsK play similar roles in coordinating cytokinesis with chromosome segregation, during growth and differentiation.
A recent study shows that SpoIIIE interacts with proteins that are connected to the cell envelope during spore development.FtsK appears to interact with proteins within all layers of the Gram-negative cell envelope.SpoIIIE and FtsK are both multifunctional and they coordinate cell-envelope remodeling with chromosome segregation.Both SpoIIIE and FtsK likely regulate peptidoglycan remodeling at the septum.Advances in cryo-electron microscopy may reveal how FtsK and SpoIIIE complexes are organized during cytokinesis.</description><subject>Bacillus subtilis - genetics</subject><subject>Bacillus subtilis - metabolism</subject><subject>Bacterial Proteins - genetics</subject><subject>Bacterial Proteins - metabolism</subject><subject>cell envelope</subject><subject>Chromatin remodeling</subject><subject>Chromosome Segregation</subject><subject>Chromosome translocations</subject><subject>Chromosomes</subject><subject>Chromosomes, Bacterial - genetics</subject><subject>Chromosomes, Bacterial - metabolism</subject><subject>Cytokinesis</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA - metabolism</subject><subject>DNA translocases</subject><subject>DNA, Bacterial - metabolism</subject><subject>E coli</subject><subject>Escherichia coli - genetics</subject><subject>Escherichia coli - metabolism</subject><subject>Escherichia coli Proteins - genetics</subject><subject>FtsK</subject><subject>Membrane Proteins - metabolism</subject><subject>Proteins</subject><subject>SpoIIIE</subject><subject>Translocase</subject><subject>Translocation</subject><issn>0966-842X</issn><issn>1878-4380</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE2LFDEQhoMo7uzqD_AiAS8e7LHy2d14WpbddXDBgwoehJBOqscM3cmY9Cz47804qwcPnooqnveleAh5wWDNgOm3u_US5jUHzuq-BuCPyIp1bddI0cFjsoJe66aT_OsZOS9lBwBKcfWUnAnZ8o5xvSLfbpbygdro6ad92mw212-oSyn7EO2ScqFppO57TnMqaUZacJtxa5eQ4u8Mxnuc0h5pxjl5nELc0hDpYN2COdhn5Mlop4LPH-YF-XJz_fnqfXP38XZzdXnXOMnl0uixlYAKrFbOqVFY0KAt9hJtO7Ry6HrfcRzY4LR0oAZvOyWEllb4sRejFxfk9al3n9OPA5bFzKE4nCYbMR2K4aoXwFvdQkVf_YPu0iHH-p3hWrdcc9HJSrET5XIqJeNo9jnMNv80DMxRvdmZqt4c1R9PVX3NvHxoPgwz-r-JP64r8O4EYFVxHzCb4gJGhz5kdIvxKfyn_hdDWZP7</recordid><startdate>20220501</startdate><enddate>20220501</enddate><creator>Chan, Helena</creator><creator>Mohamed, Ahmed M.T.</creator><creator>Grainge, Ian</creator><creator>Rodrigues, Christopher D.A.</creator><general>Elsevier Ltd</general><general>Elsevier Science Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QO</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20220501</creationdate><title>FtsK and SpoIIIE, coordinators of chromosome segregation and envelope remodeling in bacteria</title><author>Chan, Helena ; Mohamed, Ahmed M.T. ; Grainge, Ian ; Rodrigues, Christopher D.A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c424t-6f740e50a65cc5f3a0606ae94ea7b74b89d82eb1bc64c05bda853364a3df93fd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Bacillus subtilis - genetics</topic><topic>Bacillus subtilis - metabolism</topic><topic>Bacterial Proteins - genetics</topic><topic>Bacterial Proteins - metabolism</topic><topic>cell envelope</topic><topic>Chromatin remodeling</topic><topic>Chromosome Segregation</topic><topic>Chromosome translocations</topic><topic>Chromosomes</topic><topic>Chromosomes, Bacterial - genetics</topic><topic>Chromosomes, Bacterial - metabolism</topic><topic>Cytokinesis</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA - metabolism</topic><topic>DNA translocases</topic><topic>DNA, Bacterial - metabolism</topic><topic>E coli</topic><topic>Escherichia coli - genetics</topic><topic>Escherichia coli - metabolism</topic><topic>Escherichia coli Proteins - genetics</topic><topic>FtsK</topic><topic>Membrane Proteins - metabolism</topic><topic>Proteins</topic><topic>SpoIIIE</topic><topic>Translocase</topic><topic>Translocation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chan, Helena</creatorcontrib><creatorcontrib>Mohamed, Ahmed M.T.</creatorcontrib><creatorcontrib>Grainge, Ian</creatorcontrib><creatorcontrib>Rodrigues, Christopher D.A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Trends in microbiology (Regular ed.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chan, Helena</au><au>Mohamed, Ahmed M.T.</au><au>Grainge, Ian</au><au>Rodrigues, Christopher D.A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>FtsK and SpoIIIE, coordinators of chromosome segregation and envelope remodeling in bacteria</atitle><jtitle>Trends in microbiology (Regular ed.)</jtitle><addtitle>Trends Microbiol</addtitle><date>2022-05-01</date><risdate>2022</risdate><volume>30</volume><issue>5</issue><spage>480</spage><epage>494</epage><pages>480-494</pages><issn>0966-842X</issn><eissn>1878-4380</eissn><abstract>The translocation of DNA during bacterial cytokinesis is mediated by the SpoIIIE/FtsK family of proteins. These proteins ensure efficient chromosome segregation into sister cells by ATP-driven translocation of DNA and they control chromosome dimer resolution. How FtsK/SpoIIIE mediate chromosome translocation during cytokinesis in Gram-positive and Gram-negative organisms has been the subject of debate. Studies on FtsK in Escherichia coli, and recent work on SpoIIIE in Bacillus subtilis, have identified interactions between each translocase and the division machinery, supporting the idea that SpoIIIE and FtsK coordinate the final steps of cytokinesis with completion of chromosome segregation. Here we summarize and discuss the view that SpoIIIE and FtsK play similar roles in coordinating cytokinesis with chromosome segregation, during growth and differentiation.
A recent study shows that SpoIIIE interacts with proteins that are connected to the cell envelope during spore development.FtsK appears to interact with proteins within all layers of the Gram-negative cell envelope.SpoIIIE and FtsK are both multifunctional and they coordinate cell-envelope remodeling with chromosome segregation.Both SpoIIIE and FtsK likely regulate peptidoglycan remodeling at the septum.Advances in cryo-electron microscopy may reveal how FtsK and SpoIIIE complexes are organized during cytokinesis.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>34728126</pmid><doi>10.1016/j.tim.2021.10.002</doi><tpages>15</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0966-842X |
| ispartof | Trends in microbiology (Regular ed.), 2022-05, Vol.30 (5), p.480-494 |
| issn | 0966-842X 1878-4380 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2593027670 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Bacillus subtilis - genetics Bacillus subtilis - metabolism Bacterial Proteins - genetics Bacterial Proteins - metabolism cell envelope Chromatin remodeling Chromosome Segregation Chromosome translocations Chromosomes Chromosomes, Bacterial - genetics Chromosomes, Bacterial - metabolism Cytokinesis Deoxyribonucleic acid DNA DNA - metabolism DNA translocases DNA, Bacterial - metabolism E coli Escherichia coli - genetics Escherichia coli - metabolism Escherichia coli Proteins - genetics FtsK Membrane Proteins - metabolism Proteins SpoIIIE Translocase Translocation |
| title | FtsK and SpoIIIE, coordinators of chromosome segregation and envelope remodeling in bacteria |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T06%3A26%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=FtsK%20and%20SpoIIIE,%20coordinators%20of%20chromosome%20segregation%20and%20envelope%20remodeling%20in%20bacteria&rft.jtitle=Trends%20in%20microbiology%20(Regular%20ed.)&rft.au=Chan,%20Helena&rft.date=2022-05-01&rft.volume=30&rft.issue=5&rft.spage=480&rft.epage=494&rft.pages=480-494&rft.issn=0966-842X&rft.eissn=1878-4380&rft_id=info:doi/10.1016/j.tim.2021.10.002&rft_dat=%3Cproquest_cross%3E2667262384%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2667262384&rft_id=info:pmid/34728126&rft_els_id=S0966842X21002420&rfr_iscdi=true |