C‐X‐C motif chemokine ligand 1 and its receptor C‐X‐C motif chemokine receptor 2 in trigeminal ganglion contribute to nerve injury‐induced orofacial mechanical allodynia

Background Orofacial ectopic pain induced by trigeminal nerve injury is a serious complication of dental treatment. C‐X‐C motif chemokine ligand 1 (CXCL1) and its primary receptor C‐X‐C motif chemokine receptor 2 (CXCR2) contribute to the development and maintenance of neuropathic pain in the spinal...

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Veröffentlicht in:	Journal of oral rehabilitation 2022-02, Vol.49 (2), p.195-206
Hauptverfasser:	Yang, Jie, Liu, Fei, Zhang, Yan‐Yan, Lin, Jiu, Li, Yue‐Ling, Zhou, Cheng, Li, Chun‐Jie, Shen, Jie‐Fei
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveoli Animals Antagonists Chemokine CXCL1 Chemokine receptors Chemokines CXCL1 CXCR2 CXCR2 protein Hyperalgesia Immunohistochemistry inferior alveolar nerve transection Kinases Ligands mechanical allodynia Mice Mice, Inbred C57BL Nervous system Neuralgia Pain Pain perception Polymerase chain reaction Potassium channels (voltage-gated) Protein kinase C Receptors, Chemokine Receptors, Interleukin-8B Reverse transcription Signal transduction Trigeminal Ganglion Trigeminal nerve Variance analysis voltage‐gated potassium channels Western blotting
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