Intravesical Mucoadhesive Hydrogel Induces Chemoresistant Bladder Cancer Ferroptosis through Delivering Iron Oxide Nanoparticles in a Three-Tier Strategy

Bladder cancer (BCa) is the most costly solid tumor owing to its high recurrence. Relapsed cancer is known to acquire chemoresistant features after standard intravesical chemotherapy. This cancer state is vulnerable to ferroptosis, which occurs when lipid peroxides generated by iron metabolism accum...

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Veröffentlicht in:ACS applied materials & interfaces 2021-11, Vol.13 (44), p.52374-52384
Hauptverfasser: Qi, Ao, Wang, Chunyang, Ni, Shaobin, Meng, Yuyang, Wang, Tengda, Yue, Ziqi, Yang, Kaiqi, Li, Yuqian, Cheng, Zhe, Guo, Pengyu, Zhang, Cheng
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Sprache:eng
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