Inhibition of FABP4 attenuates hyperoxia‐induced lung injury and fibrosis via inhibiting TGF‐β signaling in neonatal rats

Bronchopulmonary dysplasia (BPD) is a chronic lung disease characterized by interrupted alveologenesis and alveolar simplification caused by oxygen therapy in premature infants. Metabolic dysfunction is involved in the pathogenesis of BPD. Fatty acid‐binding protein 4 (FABP4) is significantly increa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular physiology 2022-02, Vol.237 (2), p.1509-1520
Hauptverfasser:	Huang, Liang‐Ti, Chou, Hsiu‐Chu, Chen, Chung‐Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Alveoli Animals Animals, Newborn Attenuation bronchopulmonary dysplasia Bronchopulmonary Dysplasia - drug therapy Collagen (type I) Disease Models, Animal Dysplasia Exposure fatty acid binding protein fatty acid binding protein inhibitor Fatty Acid-Binding Proteins - metabolism Fatty acids fibroblast Fibrosis Health services Histology Humans Hyperoxia Hyperoxia - pathology Infant, Newborn Injury prevention Lung - pathology Lung diseases Lung Injury - pathology Neonates Pathogenesis Pulmonary fibrosis Pulmonary Fibrosis - metabolism Rats Rodents Therapeutic applications Transforming Growth Factor beta1 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!