Conditional depletion of transcriptional kinases Ctk1 and Bur1 and effects on co-transcriptional spliceosome assembly and pre-mRNA splicing

From yeast to humans, pre-mRNA splicing occurs mainly co-transcriptionally, with splicing and transcription functionally coupled such that they influence one another. The recruitment model of co-transcriptional splicing proposes that core members of the transcription elongation machinery have the po...

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Veröffentlicht in:	RNA biology 2021-11, Vol.18 (S2), p.782-793
Hauptverfasser:	Maudlin, Isabella E., Beggs, Jean D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosomal Proteins, Non-Histone - metabolism CTD Cyclin-Dependent Kinases - metabolism Gene Expression Regulation, Fungal Phosphorylation pre-mRNA splicing Protein Kinases - metabolism Research Paper RNA Precursors - genetics RNA Splicing Saccharomyces cerevisiae Proteins - metabolism serine 2 phosphorylation Spliceosomes - metabolism Transcription elongation Transcriptional Elongation Factors - metabolism yeast
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