Probing the free-state solution behavior of drugs and their tendencies to self-aggregate into nano-entities

The free-state solution behaviors of drugs profoundly affect their properties. Therefore, it is critical to properly evaluate a drug’s unique multiphase equilibrium when in an aqueous enviroment, which can comprise lone molecules, self-associating aggregate states and solid phases. To date, the full...

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Veröffentlicht in:Nature protocols 2021-11, Vol.16 (11), p.5250-5273
Hauptverfasser: LaPlante, Steven R., Roux, Valérie, Shahout, Fatma, LaPlante, Gabriela, Woo, Simon, Denk, Maria M., Larda, Sacha T., Ayotte, Yann
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Sprache:eng
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