Constant Vt Ventilation and Surfactant Dysfunction: An Overlooked Cause of Ventilator-induced Lung Injury

Ventilator-induced lung injury (VILI) is currently ascribed to volutrauma and/or atelectrauma, but the effect of constant Vt ventilation (CVtV) has received little attention. This Perspective summarizes the literature documenting that CVtV causes VILI and reviews the mechanisms by which it occurs. S...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2022-01, Vol.205 (2), p.152-160
1. Verfasser:	Albert, Richard K
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Iatrogenesis Injuries Lung diseases Medical research Positive-Pressure Respiration - adverse effects Pulmonary Surfactants - adverse effects Respiration, Artificial - adverse effects Respiratory Distress Syndrome - etiology Respiratory Distress Syndrome - physiopathology Surfactants Ventilator-Induced Lung Injury - etiology Ventilator-Induced Lung Injury - physiopathology Ventilators
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