$Association between genetic variants in oxidative stress-related genes and osteoporotic bone fracture. The Hortega follow-up study$

Association between genetic variants in oxidative stress-related genes and osteoporotic bone fracture. The Hortega follow-up study

•SNP in oxidative stress-related genes are crucial in osteoporotic bone fracture.•rs4077561 TXNRD1 SNP was the principal genetic risk factor associated with fracture.•Genetic factors are crucial in the etiopathogenesis of osteoporosis complications. The most widely accepted etiopathogenesis hypothes...

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Veröffentlicht in:	Gene 2022-01, Vol.809, p.146036-146036, Article 146036
Hauptverfasser:	Usategui-Martín, Ricardo, Pérez-Castrillón, José Luis, Mansego, María L., Lara-Hernández, Francisco, Manzano, Iris, Briongos, Laisa, Abadía-Otero, Jesica, Martín-Vallejo, Javier, García-García, Ana B., Martín-Escudero, Juan Carlos, Chaves, Felipe J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging Bone Density - genetics Bone metabolism Cross-Sectional Studies Female Follow-Up Studies Fracture Gene Frequency Genetic Predisposition to Disease Glutathione Peroxidase - genetics Humans Male Middle Aged Mitochondrial Proteins - genetics Osteoporosis Osteoporotic Fractures - genetics Oxidative stress Oxidative Stress - genetics Polymorphism, Single Nucleotide Reactive oxygen species Receptor, IGF Type 2 - genetics Spain Thioredoxin Reductase 1 - genetics Thioredoxins - genetics
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