MMP2-responsive dual-targeting drug delivery system for valence-controlled arsenic trioxide prodrug delivery against hepatic carcinoma

Preparation process of CaAs NP (A) and FA/PF-LP-CaAs (B). Schematic illustration of FA/PF-LP-CaAs for hepatocellular carcinoma therapy. [Display omitted] Arsenic trioxide (ATO) is the active ingredient in traditional Chinese medicine, i.e., Arsenic, which has shown excellent therapeutic effects on h...

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Veröffentlicht in:	International journal of pharmaceutics 2021-11, Vol.609, p.121209-121209, Article 121209
Hauptverfasser:	Li, Chaoqun, Zhang, Ke, Liu, Aidi, Yue, Tianxiang, Wei, Yinghui, Zheng, Hangsheng, Piao, Ji-Gang, Li, Fanzhu
Format:	Artikel
Sprache:	eng
Schlagworte:	Arsenic trioxide prodrug Dual targeting Hepatocellular carcinoma MMP2-responsive Valence-controlled
Online-Zugang:	Volltext
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