Pathogenic mitochondrial dysfunction and metabolic abnormalities

Metabolic commonalities are found in a wide range of diseases, acquired or inherited, with mitochondria playing key roles in all of them. [Display omitted] Herein we trace links between biochemical pathways, pathogenesis, and metabolic diseases to set the stage for new therapeutic advances. Cellular...

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Veröffentlicht in:	Biochemical pharmacology 2021-11, Vol.193, p.114809-114809, Article 114809
Hauptverfasser:	Moos, Walter H., Faller, Douglas V., Glavas, Ioannis P., Harpp, David N., Kamperi, Natalia, Kanara, Iphigenia, Kodukula, Krishna, Mavrakis, Anastasios N., Pernokas, Julie, Pernokas, Mark, Pinkert, Carl A., Powers, Whitney R., Steliou, Kosta, Tamvakopoulos, Constantin, Vavvas, Demetrios G., Zamboni, Robert J., Sampani, Konstantina
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemical pathways Diseases Disorders Dysfunction Homeostasis Metabolic abnormalities Mitochondrial diseases Pathogenesis Pathogenesis and pathogenic drivers Physiological networks Reprogramming Therapeutics
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