A program for the evaluation of 3D spectra applied to the sequential assignment of BPTI utilizing 3D TOCSY-NOESY

A program for the evaluation of 3D spectra applied to the sequential assignment of BPTI utilizing 3D TOCSY-NOESY

The determination of three-dimensional structures of proteins by NMR requires the assignment of their super(1)H NMR spectrum, performed mostly by means of 2D NMR. The main problem is to find the correct sequential connectivities, a step which is time-consuming and usually hindered by spectral overla...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of magnetic resonance (1997) 1990-01, Vol.87 (2), p.400-407
Hauptverfasser: Cieslar, C, Holak, T A, Oschkinat, H
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 407
container_issue 2
container_start_page 400
container_title Journal of magnetic resonance (1997)
container_volume 87
creator Cieslar, C
Holak, T A
Oschkinat, H
description The determination of three-dimensional structures of proteins by NMR requires the assignment of their super(1)H NMR spectrum, performed mostly by means of 2D NMR. The main problem is to find the correct sequential connectivities, a step which is time-consuming and usually hindered by spectral overlap. We want to show that the use of homonuclear 3D spectroscopy is of advantage for the automatic assignment. The advantage of using cross peaks of 3D TOCSY-NOESY spectra lies in the reduction of the number of possible nodes due to the better characterization of the connectivities.
format Article
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_25842198</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>25842198</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_258421983</originalsourceid><addsrcrecordid>eNqNjrsKwkAQRbdQ8PkPU9kFNmpILH2ijQqmsZIhTuLKZnfNbCz8eqP4AVaXC-cebkt0QzmTQZzIuCN6zHcpwzCKZVe4ObjKFhWWkNsK_I2Anqhr9MoasDlMVsCOMl8hoHNa0RW8_XJMj5qMV6gBmVVhyqZ9JotjuoPaK61eyhQfQ3pYns7B_rA-nQeinaNmGv6yL0abdbrcBs2Nxsf-UirOSGs0ZGu-jKNkOg5nyeRv8A04j0tw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>25842198</pqid></control><display><type>article</type><title>A program for the evaluation of 3D spectra applied to the sequential assignment of BPTI utilizing 3D TOCSY-NOESY</title><source>Elsevier ScienceDirect Journals Complete</source><creator>Cieslar, C ; Holak, T A ; Oschkinat, H</creator><creatorcontrib>Cieslar, C ; Holak, T A ; Oschkinat, H</creatorcontrib><description>The determination of three-dimensional structures of proteins by NMR requires the assignment of their super(1)H NMR spectrum, performed mostly by means of 2D NMR. The main problem is to find the correct sequential connectivities, a step which is time-consuming and usually hindered by spectral overlap. We want to show that the use of homonuclear 3D spectroscopy is of advantage for the automatic assignment. The advantage of using cross peaks of 3D TOCSY-NOESY spectra lies in the reduction of the number of possible nodes due to the better characterization of the connectivities.</description><identifier>ISSN: 1090-7807</identifier><language>eng</language><ispartof>Journal of magnetic resonance (1997), 1990-01, Vol.87 (2), p.400-407</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Cieslar, C</creatorcontrib><creatorcontrib>Holak, T A</creatorcontrib><creatorcontrib>Oschkinat, H</creatorcontrib><title>A program for the evaluation of 3D spectra applied to the sequential assignment of BPTI utilizing 3D TOCSY-NOESY</title><title>Journal of magnetic resonance (1997)</title><description>The determination of three-dimensional structures of proteins by NMR requires the assignment of their super(1)H NMR spectrum, performed mostly by means of 2D NMR. The main problem is to find the correct sequential connectivities, a step which is time-consuming and usually hindered by spectral overlap. We want to show that the use of homonuclear 3D spectroscopy is of advantage for the automatic assignment. The advantage of using cross peaks of 3D TOCSY-NOESY spectra lies in the reduction of the number of possible nodes due to the better characterization of the connectivities.</description><issn>1090-7807</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><recordid>eNqNjrsKwkAQRbdQ8PkPU9kFNmpILH2ijQqmsZIhTuLKZnfNbCz8eqP4AVaXC-cebkt0QzmTQZzIuCN6zHcpwzCKZVe4ObjKFhWWkNsK_I2Anqhr9MoasDlMVsCOMl8hoHNa0RW8_XJMj5qMV6gBmVVhyqZ9JotjuoPaK61eyhQfQ3pYns7B_rA-nQeinaNmGv6yL0abdbrcBs2Nxsf-UirOSGs0ZGu-jKNkOg5nyeRv8A04j0tw</recordid><startdate>19900101</startdate><enddate>19900101</enddate><creator>Cieslar, C</creator><creator>Holak, T A</creator><creator>Oschkinat, H</creator><scope>7SC</scope><scope>8FD</scope><scope>JQ2</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope></search><sort><creationdate>19900101</creationdate><title>A program for the evaluation of 3D spectra applied to the sequential assignment of BPTI utilizing 3D TOCSY-NOESY</title><author>Cieslar, C ; Holak, T A ; Oschkinat, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_258421983</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cieslar, C</creatorcontrib><creatorcontrib>Holak, T A</creatorcontrib><creatorcontrib>Oschkinat, H</creatorcontrib><collection>Computer and Information Systems Abstracts</collection><collection>Technology Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts – Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><jtitle>Journal of magnetic resonance (1997)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cieslar, C</au><au>Holak, T A</au><au>Oschkinat, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A program for the evaluation of 3D spectra applied to the sequential assignment of BPTI utilizing 3D TOCSY-NOESY</atitle><jtitle>Journal of magnetic resonance (1997)</jtitle><date>1990-01-01</date><risdate>1990</risdate><volume>87</volume><issue>2</issue><spage>400</spage><epage>407</epage><pages>400-407</pages><issn>1090-7807</issn><abstract>The determination of three-dimensional structures of proteins by NMR requires the assignment of their super(1)H NMR spectrum, performed mostly by means of 2D NMR. The main problem is to find the correct sequential connectivities, a step which is time-consuming and usually hindered by spectral overlap. We want to show that the use of homonuclear 3D spectroscopy is of advantage for the automatic assignment. The advantage of using cross peaks of 3D TOCSY-NOESY spectra lies in the reduction of the number of possible nodes due to the better characterization of the connectivities.</abstract></addata></record>
fulltext fulltext
identifier ISSN: 1090-7807
ispartof Journal of magnetic resonance (1997), 1990-01, Vol.87 (2), p.400-407
issn 1090-7807
language eng
recordid cdi_proquest_miscellaneous_25842198
source Elsevier ScienceDirect Journals Complete
title A program for the evaluation of 3D spectra applied to the sequential assignment of BPTI utilizing 3D TOCSY-NOESY
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T01%3A57%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20program%20for%20the%20evaluation%20of%203D%20spectra%20applied%20to%20the%20sequential%20assignment%20of%20BPTI%20utilizing%203D%20TOCSY-NOESY&rft.jtitle=Journal%20of%20magnetic%20resonance%20(1997)&rft.au=Cieslar,%20C&rft.date=1990-01-01&rft.volume=87&rft.issue=2&rft.spage=400&rft.epage=407&rft.pages=400-407&rft.issn=1090-7807&rft_id=info:doi/&rft_dat=%3Cproquest%3E25842198%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=25842198&rft_id=info:pmid/&rfr_iscdi=true